子宫内膜间质肉瘤中的复杂核型改变。

Complex karyotypic alterations in an endometrial stromal sarcoma.

作者信息

Hrynchak M, Horsman D, Salski C, Berean K, Benedet J L

机构信息

Division of Laboratory Medicine, British Columbia Cancer Agency, Canada.

出版信息

Cancer Genet Cytogenet. 1994 Oct;77(1):45-9. doi: 10.1016/0165-4608(94)90147-3.

DOI:10.1016/0165-4608(94)90147-3

PMID:7923082

Abstract

Cytogenetic investigation of a low-grade endometrial stromal sarcoma (ESS) revealed structural rearrangements of chromosomes 3, 6, and 7. The karyotypic findings in the few cases of ESS reported reveal recurrent involvement of both homologues of chromosome 7, with less consistent changes affecting chromosomes 6 and 17. The cytogenetic and histologic features of these uterine stromal tumors require further study.

摘要

对一例低级别子宫内膜间质肉瘤（ESS）的细胞遗传学研究显示3号、6号和7号染色体存在结构重排。已报道的少数ESS病例的核型结果显示，7号染色体的两条同源染色体均反复受累，而6号和17号染色体的变化则不太一致。这些子宫间质肿瘤的细胞遗传学和组织学特征需要进一步研究。