Institute of Virology, Vaccines and Sera, "Torlak", Vojvode Stepe 458, 11000 Belgrade, Serbia.
Environmental Protection Agency, Ruže Jovanović 27a, 11060 Beograd, Serbia.
Medicina (Kaunas). 2020 Feb 4;56(2):59. doi: 10.3390/medicina56020059.
The relationship between air pollen quantity and the sensitization of allergic patients is crucial for both the diagnosis and treatment of allergic diseases. Weather conditions influence the distribution of allergenic pollen and increases in pollen concentration may negatively affect the health of allergic patients. The aim of this study was to analyze the implementation of allergen immunotherapy with regard to air pollen concentration. : Here we examined the relationship between air pollen concentration and the usage of allergen immunotherapy in Serbia. Examination covered the period from 2015 to 2018. Measurement of airborne pollen concentration was performed with Lanzoni volumetric pollen traps. The evidence of the usage of sublingual allergen immunotherapy (SLIT) was gathered from patients with documented sensitization to specific pollen. Results: During this period tree pollens were represented with 58% ± 21% of all measured air pollen species, while pollen represented 15% ± 8% of all tree pollens. pollination peaked in April. Allergen immunotherapy to in Serbia is entirely conducted as sublingual immunotherapy and represents 47.1% ± 1.4% of issued tree pollen SLIT. The use of pollen SLIT increased by 68% from 2015 to 2018, with an even greater increase in usage recorded for SLIT-80%. This analysis shows a clear causative relationship between pollination and the type/prevalence of applied allergen immunotherapy. Information about the flowering seasons of allergenic plants is very important for people who suffer from allergy, for clinical allergologists, as well as for governing authorities. The presented data is of practical importance to the proper timing of immunotherapy initiation and of importance for urban landscaping. The obtained data can be the starting point for the instatement of a thorough epidemiological study and the inclusion of Serbia on the pollen map of Europe.
空气花粉数量与过敏患者致敏之间的关系对过敏性疾病的诊断和治疗都至关重要。天气条件影响过敏原花粉的分布，花粉浓度的增加可能会对过敏患者的健康产生负面影响。本研究旨在分析变应原免疫治疗与空气花粉浓度的关系。我们在这里检查了塞尔维亚空气花粉浓度与变应原免疫治疗使用之间的关系。检查涵盖了 2015 年至 2018 年期间。空气花粉浓度的测量是使用 Lanzoni 容量花粉收集器进行的。舌下变应原免疫治疗（SLIT）的使用证据是从对特定花粉有记录致敏的患者中收集的。结果：在此期间，树木花粉占所有测量的空气花粉物种的 58%±21%，而草花粉占所有树木花粉的 15%±8%。花粉授粉在四月达到高峰。在塞尔维亚，对花粉的变应原免疫治疗完全采用舌下免疫疗法，占所发布的树木花粉 SLIT 的 47.1%±1.4%。2015 年至 2018 年期间，花粉 SLIT 的使用增加了 68%，其中花粉 SLIT-80%的使用增加更为明显。该分析显示授粉与应用变应原免疫治疗的类型/流行率之间存在明确的因果关系。致敏植物开花季节的信息对过敏患者、临床变态反应学家以及政府当局非常重要。所提供的数据对免疫治疗开始的适当时间以及城市景观规划具有实际意义。获得的数据可以作为启动全面流行病学研究的起点，并将塞尔维亚纳入欧洲花粉地图。
