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创伤性脑损伤后的存活率随着神经外科医生的部署而提高:在伊拉克和阿富汗冲突期间比较美国和英国的军事治疗设施。

Survival after traumatic brain injury improves with deployment of neurosurgeons: a comparison of US and UK military treatment facilities during the Iraq and Afghanistan conflicts.

机构信息

Academic Department of Military Surgery and Trauma, Royal Centre for Defence Medicine, Birmingham, UK

Department of Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, Birmingham, UK.

出版信息

J Neurol Neurosurg Psychiatry. 2020 Apr;91(4):359-365. doi: 10.1136/jnnp-2019-321723. Epub 2020 Feb 7.

Abstract

INTRODUCTION

Traumatic brain injury (TBI) is the most common cause of death on the modern battlefield. In recent conflicts in Iraq and Afghanistan, the US typically deployed neurosurgeons to medical treatment facilities (MTFs), while the UK did not. Our aim was to compare the incidence, TBI and treatment in US and UK-led military MTF to ascertain if differences in deployed trauma systems affected outcomes.

METHODS

The US and UK Combat Trauma Registries were scrutinised for patients with HI at deployed MTFs between March 2003 and October 2011. Registry datasets were adapted to stratify TBI using the Mayo Classification System for Traumatic Brain Injury Severity. An adjusted multiple logistic regression model was performed using fatality as the binomial dependent variable and treatment in a US-MTF or UK-MTF, surgical decompression, US military casualty and surgery performed by a neurosurgeon as independent variables.

RESULTS

15 031 patients arrived alive at military MTF after TBI. Presence of a neurosurgeon was associated with increased odds of survival in casualties with moderate or severe TBI (p<0.0001, OR 2.71, 95% CI 2.34 to 4.73). High injury severity (Injury Severity Scores 25-75) was significantly associated with a lower survival (OR 4×10, 95% CI 1.61×10 to 110.6×10, p<0.001); however, having a neurosurgeon present still remained significantly positively associated with survival (OR 3.25, 95% CI 2.71 to 3.91, p<0.001).

CONCLUSIONS

Presence of neurosurgeons increased the likelihood of survival after TBI. We therefore recommend that the UK should deploy neurosurgeons to forward military MTF whenever possible in line with their US counterparts.

摘要

引言

创伤性脑损伤(TBI)是现代战场上最常见的死亡原因。在最近的伊拉克和阿富汗冲突中,美国通常会向医疗救治机构(MTF)派遣神经外科医生,而英国则没有。我们的目的是比较美英领导的军事 MTF 中创伤性脑损伤的发生率、TBI 和治疗情况,以确定部署的创伤系统的差异是否影响结果。

方法

对 2003 年 3 月至 2011 年 10 月期间部署在军事 MTF 的 HI 患者的美国和英国战斗创伤登记处进行了仔细审查。登记处数据集经过改编,使用 Mayo 创伤性脑损伤严重程度分类系统对 TBI 进行分层。使用死亡作为二项因变量和在 US-MTF 或 UK-MTF 中治疗、减压手术、美国军事伤员和神经外科医生进行的手术作为独立变量,进行了调整后的多变量逻辑回归模型。

结果

15031 名 TBI 后存活到达军事 MTF 的患者。有神经外科医生存在与中度或重度 TBI 伤员的存活几率增加相关(p<0.0001,OR 2.71,95%CI 2.34 至 4.73)。高损伤严重程度(损伤严重程度评分 25-75)与较低的存活率显著相关(OR 4×10,95%CI 1.61×10 至 110.6×10,p<0.001);然而,有神经外科医生存在仍然与存活显著正相关(OR 3.25,95%CI 2.71 至 3.91,p<0.001)。

结论

神经外科医生的存在增加了 TBI 后存活的可能性。因此,我们建议英国应按照美国的做法,尽可能向前进的军事 MTF 派遣神经外科医生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69c6/7147183/a50cb94494d7/jnnp-2019-321723f01.jpg

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