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后路骶骨肿瘤切除术治疗脊索瘤患者的 ACS-NSQIP 外科风险计算器能否预测术后并发症?

Can the ACS-NSQIP surgical risk calculator predict postoperative complications in patients undergoing sacral tumor resection for chordoma?

机构信息

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.

University Musculoskeletal Oncology Unit Mount Sinai Hospital, Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, Toronto, Canada.

出版信息

J Surg Oncol. 2020 May;121(6):1036-1041. doi: 10.1002/jso.25865. Epub 2020 Feb 7.

DOI:10.1002/jso.25865
PMID:32034772
Abstract

BACKGROUND AND OBJECTIVES

The ACS-NSQIP surgical risk calculator is an online tool that estimates the risk of postoperative complications. Sacrectomies for chordoma are associated with a high rate of complications. This study was to determine if the ACS-NSQIP calculator can predict postoperative complications following sacrectomy.

METHODS

Sixty-five (42 male, 23 female) patients who underwent sacrectomy were analyzed using the Current Procedural Terminology (CPT) codes: 49215 (excision of presacral/sacral tumor), 63001 (laminectomy of sacral vertebrae), 63728 (laminectomy for biopsy/excision of sacral neoplasm) and 63307 (sacral vertebral corpectomy for intraspinal lesion). The predicted rates of complications were compared to the observed rates.

RESULTS

Complications were noted in 44 (68%) patients. Of the risk factors available to input to the ACS-NSQIP calculator, tobacco use (OR, 20.4; P < .001) was predictive of complications. The predicted risk of complications based off the CPT codes were: 49215 (16%); 63011 (6%); 63278 (11%) and 63307 (15%). Based on ROC curves, the use of the ACS-NSQIP score were poor predictors of complications (49215, AUC 0.65); (63011, AUC 0.66); (63307, AUC 0.67); (63278, AUC 0.64).

CONCLUSION

The ACS-NSQIP calculator was a poor predictor of complications and was marginally better than a coin flip in its ability to predict complications following sacrectomy for chordoma.

摘要

背景与目的

ACS-NSQIP 手术风险计算器是一种在线工具,可用于估计术后并发症的风险。脊索瘤的骶骨切除术与高并发症发生率相关。本研究旨在确定 ACS-NSQIP 计算器是否可预测脊索瘤患者骶骨切除术后的并发症。

方法

分析了 65 例(42 例男性,23 例女性)接受骶骨切除术的患者,使用的 CPT 代码包括:49215(切除骶前/骶骨肿瘤)、63001(骶骨椎板切除术)、63728(切除活检/骶骨肿瘤)和 63307(脊柱内病变的骶骨椎体切除术)。将预测的并发症发生率与观察到的发生率进行比较。

结果

44 例(68%)患者出现并发症。在可输入到 ACS-NSQIP 计算器的风险因素中,吸烟(OR,20.4;P <.001)与并发症相关。基于 CPT 代码预测的并发症风险分别为:49215(16%)、63011(6%)、63278(11%)和 63307(15%)。基于 ROC 曲线,ACS-NSQIP 评分的使用对并发症的预测效果较差(49215,AUC 0.65);(63011,AUC 0.66);(63307,AUC 0.67);(63278,AUC 0.64)。

结论

ACS-NSQIP 计算器对并发症的预测效果较差,在预测脊索瘤患者骶骨切除术后并发症方面,其预测能力略优于抛硬币。

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