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美国外科医师学会国家外科质量改进计划(ACS-NSQIP)手术风险计算器在接受腰椎手术的老年患者中的预测效度

Predictive validity of the ACS-NSQIP surgical risk calculator in geriatric patients undergoing lumbar surgery.

作者信息

Wang Xiao, Hu Yanting, Zhao Binjiang, Su Yue

机构信息

Beijing Shijitan Hospital Anesthesiology, Capital Medical University, Beijing, China.

出版信息

Medicine (Baltimore). 2017 Oct;96(43):e8416. doi: 10.1097/MD.0000000000008416.

Abstract

The risk calculator of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) has been shown to be useful in predicting postoperative complications. In this study, we aimed to evaluate the predictive value of the ACS-NSQIP calculator in geriatric patients undergoing lumbar surgery.A total of 242 geriatric patients who underwent lumbar surgery between January 2014 and December 2016 were included. Preoperative clinical information was retrospectively reviewed and entered into the ACS-NSQIP calculator. The predictive value of the ACS-NSQIP model was assessed using the Hosmer-Lemeshow test, Brier score (B), and receiver operating characteristics (ROC, also referred C-statistic) curve analysis. Additional risk factors were calculated as surgeon-adjusted risk including previous cardiac event and cerebrovascular disease.Preoperative risk factors including age (P = .004), functional independence (P = 0), American Society of Anesthesiologists class (ASA class, P = 0), dyspnea (P = 0), dialysis (P = .049), previous cardiac event (P = .001), and history of cerebrovascular disease (P = 0) were significantly associated with a greater incidence of postoperative complications. Observed and predicted incidence of postoperative complications was 43.8% and 13.7% (±5.9%) (P < .01), respectively. The Hosmer-Lemeshow test demonstrated adequate predictive accuracy of the ACS-NSQIP model for all complications. However, Brier score showed that the ACS-NSQIP model could not accurately predict risk of all (B = 0.321) or serious (B = 0.241) complications, although it accurately predicted the risk of death (B = 0.0072); this was supported by ROC curve analysis. The ROC curve also showed that the model had high sensitivity and specificity for predicting renal failure and readmission.The ACS-NSQIP surgical risk calculator is not an accurate tool for the prediction of postoperative complications in geriatric Chinese patients undergoing lumbar surgery.

摘要

美国外科医师学会国家外科质量改进计划(ACS - NSQIP)的风险计算器已被证明在预测术后并发症方面很有用。在本研究中,我们旨在评估ACS - NSQIP计算器对接受腰椎手术的老年患者的预测价值。

纳入了2014年1月至2016年12月期间接受腰椎手术的242例老年患者。对术前临床信息进行回顾性审查并录入ACS - NSQIP计算器。使用Hosmer - Lemeshow检验、Brier评分(B)和受试者工作特征(ROC,也称为C统计量)曲线分析来评估ACS - NSQIP模型的预测价值。计算包括既往心脏事件和脑血管疾病在内的经外科医生调整的额外风险因素。

术前风险因素包括年龄(P = 0.004)、功能独立性(P = 0)、美国麻醉医师协会分级(ASA分级,P = 0)、呼吸困难(P = 0)、透析(P = 0.049)、既往心脏事件(P = 0.001)和脑血管疾病史(P = 0)与术后并发症发生率较高显著相关。术后并发症的观察发生率和预测发生率分别为43.8%和13.7%(±5.9%)(P < 0.01)。Hosmer - Lemeshow检验表明ACS - NSQIP模型对所有并发症具有足够的预测准确性。然而,Brier评分显示,尽管ACS - NSQIP模型准确预测了死亡风险(B = 0.0072),但它不能准确预测所有(B = 0.321)或严重(B = 0.241)并发症的风险;ROC曲线分析支持了这一点。ROC曲线还表明该模型在预测肾衰竭和再入院方面具有高敏感性和特异性。

ACS - NSQIP手术风险计算器对于预测接受腰椎手术的中国老年患者的术后并发症而言并非准确工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/391e/5671873/2cda86ea9667/medi-96-e8416-g002.jpg

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