Departamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México 04510, Mexico.
Departamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México 04510, Mexico.
Fungal Genet Biol. 2020 Apr;137:103338. doi: 10.1016/j.fgb.2020.103338. Epub 2020 Feb 5.
The endoplasmic reticulum (ER) is composed of distinct structural domains that perform diverse essential functions, including the synthesis of membrane lipids and proteins of the cell endomembrane system. The polarized growth of fungal hyphal cells depends on a polarized secretory system, which delivers vesicles to the hyphal apex for localized cell expansion, and that involves a polarized distribution of the secretory compartments, including the ER. Here we show that, additionally, the ER of the ascomycete Podospora anserina possesses a peripheral ER domain consisting of highly dynamic pleomorphic ER sub-compartments, which are specifically associated with the polarized growing apical hyphal cells.
内质网（ER）由不同的结构域组成，具有多种重要的功能，包括细胞内膜系统的膜脂质和蛋白质的合成。真菌菌丝细胞的极化生长依赖于一个极化的分泌系统，该系统将囊泡输送到菌丝顶端，以进行局部细胞扩张，这涉及到分泌隔室的极化分布，包括内质网。在这里，我们表明，此外，子囊菌 Podospora anserina 的内质网还具有一个外周内质网域，该域由高度动态的多形内质网亚区组成，这些亚区与极化生长的顶端菌丝细胞特异性相关。
