Cooper W C
Environ Health Perspect. 1988 Jun;78:61-3. doi: 10.1289/ehp.887861.
This report is based on an analysis of deaths in 4519 battery plant workers and 2300 lead production or smelter workers during the years 1947 to 1980. Causes were coded to the seventh (1955) revision of the International Classification of Diseases. There were significant excess deaths for "other hypertensive disease" (444-447) and "chronic nephritis" (592-594) in both cohorts, the standardized mortality ratios (SMRs) being 320 and 475, respectively, for the former causes and 222 and 265 for the latter. Proportionate mortality analysis, which adjusted for race, also showed elevated ratios, 241 and 388 for the former causes and 296 and 186 for the latter. Deaths from other hypertension-related diseases did not show comparable excesses. Renal cancer deaths were fewer than expected, SMRs being 41 and 74, respectively.
本报告基于对1947年至1980年间4519名电池厂工人和2300名铅生产或冶炼厂工人死亡情况的分析。病因按照《国际疾病分类》第七版(1955年)进行编码。两个队列中,“其他高血压疾病”(444 - 447)和“慢性肾炎”(592 - 594)的死亡人数显著超标,前一类病因的标准化死亡比(SMR)分别为320和475,后一类病因的标准化死亡比分别为222和265。经种族调整的比例死亡率分析也显示出比率升高,前一类病因的比率为241和388,后一类病因的比率为296和186。其他与高血压相关疾病的死亡人数未显示出类似的超标情况。肾癌死亡人数低于预期,标准化死亡比分别为41和74。