Critical Care Western, London Health Sciences Centre, Western University, London, Ontario, Canada; Department of Medicine, Division of Emergency Medicine, London Health Sciences Centre, Western University, London, Ontario, Canada.
Department of Medicine, Division of Cardiology, Section of Heart Failure, London Health Sciences Centre, Western University, London, Ontario, Canada.
Can J Cardiol. 2020 Feb;36(2):313-316. doi: 10.1016/j.cjca.2019.11.034. Epub 2019 Dec 20.
Left ventricular assist devices (LVADs) improve survival and quality of life in refractory end-stage heart failure. However, the therapy itself is associated with some degree of morbidity and mortality at highest risk during the first 30 days postimplantation. Management of the patient with a freshly implanted LVAD requires an in-depth understanding of the acute postimplant period and common critical care issues including coagulopathy, hemodynamic lability, and metabolic derangements. This requires meticulous hemostatic control and a firm understanding of hemodynamic principles that focus on optimizing end-organ perfusion, right-ventricular function, and measured LVAD titration. This contemporary practical guide to management of the acute postimplant LVAD patient includes a focused approach to troubleshooting common LVAD issues that may arise from the operating room to discharge from critical care.
左心室辅助装置(LVAD)可改善难治性终末期心力衰竭患者的生存率和生活质量。然而,该治疗本身与一定程度的发病率和死亡率相关,在植入后的前 30 天内风险最高。管理新植入 LVAD 的患者需要深入了解急性植入后期间和常见的关键护理问题,包括凝血功能障碍、血流动力学不稳定和代谢紊乱。这需要细致的止血控制和对专注于优化终末器官灌注、右心室功能和测量 LVAD 滴定的血流动力学原则的深刻理解。本实用指南对急性植入后 LVAD 患者的管理进行了全面介绍,包括从手术室到关键护理出院期间可能出现的常见 LVAD 问题的故障排除方法。