Woyciechowska J, Breschkin A M, Rapp F
Lab Invest. 1977 Mar;36(3):233-6.
The localization of measles virus antigens in hamster brains inoculated with a temperature-sensitive mutant of measles virus r its revertant was studied by immunofluorescence. We found significantly less virus antigen in mutant-inoculated than in revertant-inoculated brains. In mutant-inoculated brains the virus antigens were very often found in the meninges. Possible mechanisms for the development of experimental hydrocephalus and meningoencephalitis are discussed.
通过免疫荧光法研究了接种麻疹病毒温度敏感突变株及其回复株的仓鼠脑中麻疹病毒抗原的定位。我们发现,接种突变株的脑内病毒抗原明显少于接种回复株的脑内。在接种突变株的脑内,病毒抗原常出现在脑膜中。文中讨论了实验性脑积水和脑膜脑炎发生的可能机制。