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-阴性黏膜相关淋巴组织淋巴瘤:两例危及生命的上消化道出血病例系列报道

-Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal Bleeding.

作者信息

Kim Seo Hyun, Soliman Youssef, Chitnavis Vikas N, Chitnavis Maithili V

机构信息

Virginia Tech Carilion School of Medicine, Roanoke, VA, USA.

Gastroenterology, City of Hope Phoenix, Goodyear, AZ, USA.

出版信息

Case Rep Gastrointest Med. 2023 Mar 23;2023:8244696. doi: 10.1155/2023/8244696. eCollection 2023.

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma is a common cause of gastric lymphoma. Although most cases are associated with an infection, approximately 10% are -negative. Patients with gastric MALT lymphoma are usually asymptomatic or present with nonspecific symptoms such as abdominal pain, dyspepsia, weight loss, and occult gastrointestinal bleeding. In this report, we describe two patients with -negative MALT lymphoma who both presented with acute upper gastrointestinal bleeding that led to hemodynamic instability. After resuscitation, emergent endoscopy was performed. Both patients had the (11; 18) (q21; q21) translocation, which prompted direct treatment by radiotherapy.

摘要

黏膜相关淋巴组织(MALT)淋巴瘤是胃淋巴瘤的常见病因。尽管大多数病例与感染有关,但约10%为阴性。胃MALT淋巴瘤患者通常无症状或表现为非特异性症状,如腹痛、消化不良、体重减轻和隐匿性胃肠道出血。在本报告中,我们描述了两名阴性MALT淋巴瘤患者,他们均因急性上消化道出血导致血流动力学不稳定。复苏后,进行了急诊内镜检查。两名患者均有(11;18)(q21;q21)易位,这促使采用放疗进行直接治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5343/10063354/bc9a402a7655/CRIGM2023-8244696.001.jpg

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