genotyping in Caucasian patients can help to optimise thiopurine treatment in patients with inflammatory bowel disease.
作者信息
Coenen Marieke J H
机构信息
Radboud University Medical Center, Radboud Institute for Health Sciences, Department of Human Genetics, Nijmegen, The Netherlands.
出版信息
Transl Gastroenterol Hepatol. 2019 Dec 12;4:81. doi: 10.21037/tgh.2019.11.09. eCollection 2019.
Abstract
摘要
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JAMA. 2019 Feb 26;321(8):773-785. doi: 10.1001/jama.2019.0709.
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Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry.NUDT15 基因对欧洲血统患者严重巯嘌呤相关血液毒性的影响。
Genet Med. 2019 Sep;21(9):2145-2150. doi: 10.1038/s41436-019-0448-7. Epub 2019 Feb 7.
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Clin Pharmacol Ther. 2019 May;105(5):1091-1094. doi: 10.1002/cpt.1268. Epub 2018 Dec 4.
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