Department of Chemistry, Zhejiang University, Hangzhou 310027, China.
Chem Commun (Camb). 2020 Feb 20;56(15):2229-2239. doi: 10.1039/d0cc00068j.
In recent years, metal-catalysed asymmetric sequential double hydrofunctionalization of alkynes (ASDHA) has emerged as a powerful strategy to construct valuable chiral products in an atom- and pot-economic manner utilizing readily available feedstocks. In this feature article, recent progress made in this field will be overviewed. Attention will be given to the background, substrate scopes, applications, advances and mechanistic investigations of various asymmetric sequential double hydrofunctionalizations of alkynes.
近年来，金属催化的炔烃不对称串联双官能化（ASDHA）已成为一种利用易得原料以原子经济性和过程经济性构建有价值手性产物的有力策略。本文将综述该领域的最新进展。重点关注各种炔烃不对称串联双官能化的背景、底物范围、应用、进展和反应机理研究。
Zotero 插件