Piao Cindy, Koul Abhinav, Gui Dorina, Chen Ling-Xin, Sarkar Souvik
Department of Internal Medicine, Sacramento, CA.
Division of Gastroenterology and Hepatology, Sacramento, CA.
ACG Case Rep J. 2019 Dec 12;6(12):e00257. doi: 10.14309/crj.0000000000000257. eCollection 2019 Dec.
Noncirrhotic portal hypertension (NCPH) is a well-known clinical entity, but often underdiagnosed. One of the common causes of NCPH is nodular regenerative hyperplasia (NRH) that presents as nodularity with features of portal hypertension and thus often diagnosed as cirrhosis. Although NRH has no histologic fibrosis, the liver synthetic function remains intact; thus, clinical diagnosis is essential because management may differ from cirrhosis. We were asked to consult in this series of 4 patients who had new-onset ascites after kidney transplantation and were diagnosed with NCPH from NRH.
非肝硬化性门静脉高压症(NCPH)是一种众所周知的临床病症,但常常诊断不足。NCPH的常见病因之一是结节性再生性增生(NRH),其表现为具有门静脉高压特征的结节,因此常被诊断为肝硬化。尽管NRH没有组织学纤维化,但肝脏合成功能仍保持完好;因此,临床诊断至关重要,因为其治疗方法可能与肝硬化不同。我们受邀对这4例肾移植后新发腹水且被诊断为NRH所致NCPH的患者进行会诊。