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深度卷积神经网络在双能胸部X光片分类中实现高效工作流程:对6500多张临床X光片的分析

Deep convolutional neural networks in the classification of dual-energy thoracic radiographic views for efficient workflow: analysis on over 6500 clinical radiographs.

作者信息

Crosby Jennie, Rhines Thomas, Li Feng, MacMahon Heber, Giger Maryellen

机构信息

The University of Chicago, Department of Radiology, Chicago, Illinois, United States.

出版信息

J Med Imaging (Bellingham). 2020 Jan;7(1):016501. doi: 10.1117/1.JMI.7.1.016501. Epub 2020 Feb 3.

DOI:10.1117/1.JMI.7.1.016501
PMID:32042858
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6995870/
Abstract

DICOM header information is frequently used to classify medical image types; however, if a header is missing fields or contains incorrect data, the utility is limited. To expedite image classification, we trained convolutional neural networks (CNNs) in two classification tasks for thoracic radiographic views obtained from dual-energy studies: (a) distinguishing between frontal, lateral, soft tissue, and bone images and (b) distinguishing between posteroanterior (PA) or anteroposterior (AP) chest radiographs. CNNs with AlexNet architecture were trained from scratch. 1910 manually classified radiographs were used for training the network to accomplish task (a), then tested with an independent test set (3757 images). Frontal radiographs from the two datasets were combined to train a network to accomplish task (b); tested using an independent test set of 1000 radiographs. ROC analysis was performed for each trained CNN with area under the curve (AUC) as a performance metric. Classification between frontal images (AP/PA) and other image types yielded an AUC of 0.997 [95% confidence interval (CI): 0.996, 0.998]. Classification between PA and AP radiographs resulted in an AUC of 0.973 (95% CI: 0.961, 0.981). CNNs were able to rapidly classify thoracic radiographs with high accuracy, thus potentially contributing to effective and efficient workflow.

摘要

DICOM头部信息经常用于对医学图像类型进行分类;然而,如果头部缺少字段或包含错误数据,其效用就会受到限制。为了加快图像分类速度,我们针对从双能研究中获得的胸部X光片视图,在两项分类任务中训练了卷积神经网络(CNN):(a)区分正位、侧位、软组织和骨骼图像;(b)区分后前位(PA)或前后位(AP)胸部X光片。具有AlexNet架构的CNN是从零开始训练的。使用1910张人工分类的X光片来训练网络以完成任务(a),然后用一个独立测试集(3757张图像)进行测试。将两个数据集中的正位X光片合并起来训练一个网络以完成任务(b);使用一个包含1000张X光片的独立测试集进行测试。对每个训练好的CNN进行ROC分析,将曲线下面积(AUC)作为性能指标。正位图像(AP/PA)与其他图像类型之间的分类产生的AUC为0.997 [95%置信区间(CI):0.996,0.998]。PA和APX光片之间的分类产生的AUC为0.973(95%CI:0.961,0.981)。CNN能够快速且高精度地对胸部X光片进行分类,从而可能有助于实现高效的工作流程。

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