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颈椎前路椎间盘切除融合术中插入前凸椎间融合器后的影像学结果

Radiological outcomes following hyperlordotic cage insertion in anterior cervical discectomy and fusion.

作者信息

Li Dianna, Poulgrain Katherine, Kam Andrew

机构信息

Department of Neurosurgery, Westmead Public Hospital, Westmead NSW, Australia.

Department of Neurosurgery, Westmead Private Hospital, Westmead NSW, Australia.

出版信息

J Spine Surg. 2019 Dec;5(4):404-412. doi: 10.21037/jss.2019.10.08.

Abstract

BACKGROUND

Cervical alignment is associated with myelopathy and quality of life. Anterior cervical discectomy and fusion (ACDF) aims to decompress neural structures and optimise cervical alignment. This study examines the quantitative impact of the hyperlordotic 15° ACDF cage on cervical alignment, and compares it to that of the standard lordosis cage.

METHODS

A retrospective analysis of radiographical parameters of cervical alignment was conducted in 80 consecutive ACDF patients from two institutions between 2013 and 2017. Forty received 15° cages, 40 received standard cages. Pre- and post-operative Cobb angles and sagittal vertical axes (SVA) were generated from radiographical imaging utilising the Surgimap program. Changes in lordosis and SVA were compared within and between groups, and the significance of the change evaluated using the Student -test.

RESULTS

In both groups, post-operative device level, segmental, and global Cobb angles were superior to preoperative values (P<0.05), especially among patients with preoperative kyphosis (P<0.05). Trends suggested greater changes in lordosis in the 15° group, but they did not reach statistical significance (P=0.06-0.23). However, subgroup analyses indicated greater device level Cobb angle change in patients less than 65 yo (P=0.049), and those with preoperative lordosis (P=0.003). Neither standard nor hyperlordotic cages significantly improved SVA in this study.

CONCLUSIONS

Hyperlordotic and standard cages both improve cervical lordosis segmentally and globally. Hyperlordotic cages were not shown to be statistically superior to standard cages in this study. Prospective studies featuring consistent imaging modalities are necessary to further delineate their utility.

摘要

背景

颈椎排列与脊髓病和生活质量相关。颈椎前路椎间盘切除融合术(ACDF)旨在减压神经结构并优化颈椎排列。本研究探讨了前凸角度为15°的ACDF椎间融合器对颈椎排列的量化影响,并将其与标准前凸椎间融合器进行比较。

方法

对2013年至2017年间来自两个机构的80例连续接受ACDF手术的患者的颈椎排列影像学参数进行回顾性分析。40例患者接受15°椎间融合器,40例患者接受标准椎间融合器。利用Surgimap程序从影像学图像中生成术前和术后的Cobb角和矢状垂直轴(SVA)。比较组内和组间前凸和SVA的变化,并使用学生t检验评估变化的显著性。

结果

两组患者术后器械节段、节段间和整体Cobb角均优于术前值(P<0.05),尤其是术前存在后凸的患者(P<0.05)。趋势表明15°组的前凸变化更大,但未达到统计学显著性(P=0.06-0.23)。然而,亚组分析表明,年龄小于65岁的患者(P=0.049)以及术前存在前凸的患者(P=0.003)的器械节段Cobb角变化更大。在本研究中,标准椎间融合器和前凸角度增加的椎间融合器均未显著改善SVA。

结论

前凸角度增加的椎间融合器和标准椎间融合器均能在节段和整体上改善颈椎前凸。在本研究中,前凸角度增加的椎间融合器在统计学上并不优于标准椎间融合器。需要采用一致成像方式的前瞻性研究来进一步明确它们的效用。

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