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当代癌症 III 期随机对照试验中具有时间事件结局的统计检验/估计方法。

Statistical Test/Estimation Methods Used in Contemporary Phase III Cancer Randomized Controlled Trials with Time-to-Event Outcomes.

机构信息

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

Department of Data Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

出版信息

Oncologist. 2020 Feb;25(2):91-93. doi: 10.1634/theoncologist.2019-0464. Epub 2019 Nov 19.

DOI:10.1634/theoncologist.2019-0464
PMID:32043795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7011662/
Abstract

There exist a wide variety of statistical methods for clinical trials. Despite decades of clinical trial research, little is known about which methods are used in data analysis practice of the real world. This review describes the evidence of existing practices on survival data analysis and identifies potential opportunities to improve them.

摘要

临床试验中存在着各种各样的统计方法。尽管已经进行了几十年的临床试验研究，但对于在现实世界的数据分析实践中使用哪些方法，人们知之甚少。本综述描述了生存数据分析中现有实践的证据，并确定了改进这些实践的潜在机会。

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