College of Chemistry, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin 300071, China; College of Chemistry and Biology Engineering, Hechi University, Yizhou 546300, China.
College of Chemistry, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin 300071, China.
J Chromatogr A. 2020 May 10;1618:460898. doi: 10.1016/j.chroma.2020.460898. Epub 2020 Jan 18.
A functionalized magnetic covalent organic framework containing the nitro groups (FeO@COF-(NO)) with core-shell structure was synthesized for magnetic solid phase extraction (MSPE) of six neonicotinoid insecticides residue in vegetable samples. The structure of FeO@COF-(NO) was investigated by various characterization techniques. The FeO@COF-(NO) exhibits the excellent thermal and chemical stability, high surface area (254.72 m g), total pore volume (0.19 cm g), high magnetic responsivity (27.7 emu g), which can be used as an ideal adsorbent for rapid isolation and enrichment of target analytes. A sensitive method was developed by using FeO@COF-(NO)-based MSPE coupled with HPLC with UV detection. It offered good linearity within the range of 0.1-30 ng mL, low limits of detection (S/N = 3) of 0.02-0.05 ng mL. Furthermore, high enrichment factors of 170-250 for six neonicotinoid insecticides were obtained. The applicability of FeO@COF-(NO) is demonstrated for measuring trace neonicotinoid residues in vegetable samples with satisfactory recoveries, which ranged from 77.5 to 110.2%. The results indicated that the FeO@COF-(NO) microspheres offer great potential for efficient extraction of neonicotinoid insecticides from complex samples.
一种含硝基基团的功能化磁性共价有机骨架（FeO@COF-(NO)），具有核壳结构，被合成用于磁性固相萃取（MSPE）蔬菜样品中六种新烟碱类杀虫剂残留。通过各种表征技术研究了 FeO@COF-(NO)的结构。FeO@COF-(NO) 表现出优异的热稳定性和化学稳定性、高表面积（254.72 m g）、总孔体积（0.19 cm g）、高磁响应性（27.7 emu g），可作为快速分离和富集目标分析物的理想吸附剂。采用基于 FeO@COF-(NO) 的 MSPE 与 HPLC-UV 检测相结合的方法，建立了一种灵敏的方法。该方法在 0.1-30 ng mL 的范围内呈现良好的线性，检测限（S/N = 3）低至 0.02-0.05 ng mL。此外，六种新烟碱类杀虫剂的富集因子高达 170-250。FeO@COF-(NO) 的适用性通过对蔬菜样品中痕量新烟碱类残留的测量得到了验证，回收率在 77.5%至 110.2%之间。结果表明，FeO@COF-(NO)微球为从复杂样品中高效提取新烟碱类杀虫剂提供了巨大潜力。
