Wang Yudan, Fu Yanwei, Wang Yunyun, Lu Qian, Ruan Haonan, Luo Jiaoyang, Yang Meihua
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
Department of Pharmacy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Food Chem X. 2022 Jun 22;15:100375. doi: 10.1016/j.fochx.2022.100375. eCollection 2022 Oct 30.
In recent years, the residues of neonicotinoid insecticide in food and environmental samples have attracted extensive attention. Neonicotinoids have many adverse effects on human health, such as cancer, chronic disease, birth defects, and infertility. They have substantial toxicity to some non-target organisms (especially bees). Hence, monitoring the residues of neonicotinoid insecticides in foodstuffs is necessary to guarantee public health and ecological stability. This review aims to summarize and assess the metabolic features, residue status, sample pretreatment methods (solid-phase extraction (SPE), Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS), and some novel pretreatment methods), and detection methods (instrument detection, immunoassay, and some innovative detection methods) for neonicotinoid insecticide residues in food and environmental samples. This review provides detailed references and discussion for the analysis of neonicotinoid insecticide residues, which can effectively promote the establishment of innovative detection methods for neonicotinoid insecticide residues.
近年来，新烟碱类杀虫剂在食品和环境样品中的残留引起了广泛关注。新烟碱类对人类健康有许多不利影响，如癌症、慢性病、出生缺陷和不孕不育。它们对一些非靶标生物（尤其是蜜蜂）具有显著毒性。因此，监测食品中新烟碱类杀虫剂的残留对于保障公众健康和生态稳定是必要的。本综述旨在总结和评估食品和环境样品中新烟碱类杀虫剂残留的代谢特征、残留状况、样品预处理方法（固相萃取（SPE）、快速、简便、廉价、有效、耐用和安全（QuEChERS）以及一些新型预处理方法）和检测方法（仪器检测、免疫分析和一些创新检测方法）。本综述为新烟碱类杀虫剂残留分析提供了详细的参考文献和讨论，可有效推动新烟碱类杀虫剂残留创新检测方法的建立。
