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行为癌痛干预随机临床试验中干预疗程完成情况的预测因素。

Predictors of Intervention Session Completion in a Randomized Clinical Trial of a Behavioral Cancer Pain Intervention.

机构信息

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA.

Miller School of Medicine, University of Miami, Coral Gables, Florida, USA.

出版信息

J Pain Symptom Manage. 2020 Jun;59(6):1268-1277. doi: 10.1016/j.jpainsymman.2020.01.020. Epub 2020 Feb 8.

Abstract

CONTEXT

Some patients with cancer are able to complete psychosocial pain management intervention sessions, and others find it difficult to do so.

OBJECTIVES

Conduct a secondary analysis of a randomized clinical trial (N = 178) that compared delivery formats (in-person vs. videoconference) of a pain coping skills training (PCST) intervention for patients with cancer to examine if intervention session completion predicts postintervention outcomes of pain severity and interference, psychological distress, physical well-being, and pain self-efficacy; and identify predictors (i.e., demographics, medical characteristics, baseline outcome scores) of session completion.

METHODS

Session completion (i.e., completing all four sessions vs. missing at least one session) was tested as a predictor of postintervention outcomes. Predictors of session completion were then examined.

RESULTS

In both study conditions combined, PCST session completion predicted improvement from baseline to postintervention in pain severity (β = -0.27; P = 0.03), pain interference (β = -0.25; P = 0.048), and pain self-efficacy (β = 0.23; P = 0.07). Participants in the videoconference condition were significantly more likely than those in the in-person condition to complete all sessions (83% vs. 65%; P = 0.006). Participants with at least some college education (odds ratio [OR] 4.36; P = 0.04), a diagnosis of breast cancer (OR 6.73; P = 0.04), and higher levels of pain self-efficacy (OR 2.32; P = 0.02) were more likely to complete videoconference sessions. Participants who lived closer to the medical center (OR 0.64; P = 0.07), had early stage cancer (OR 3.82; P = 0.07), and fewer medical comorbidities (OR 0.59; P = 0.04) were more likely to complete in-person sessions.

CONCLUSION

Completing PCST sessions is important for improving pain outcomes. Efforts to increase session completion (e.g., videoconference delivery) should be considered.

摘要

背景

一些癌症患者能够完成心理社会疼痛管理干预课程,但也有一些患者发现难以完成。

目的

对一项随机临床试验(N=178)进行二次分析,该试验比较了面对面与视频会议两种方式提供的疼痛应对技能培训(PCST)干预,以评估干预课程完成情况是否预测干预后疼痛严重程度和干扰、心理困扰、身体幸福感和疼痛自我效能的结果;并确定课程完成情况的预测因素(即人口统计学、医学特征、基线结果评分)。

方法

将课程完成情况(即完成所有 4 次课程与至少错过 1 次课程)作为预测干预后结果的指标进行测试。然后检查课程完成情况的预测因素。

结果

在两种研究条件相结合的情况下,PCST 课程完成情况预测了疼痛严重程度(β=-0.27;P=0.03)、疼痛干扰(β=-0.25;P=0.048)和疼痛自我效能(β=0.23;P=0.07)从基线到干预后的改善。与面对面组相比,视频会议组完成所有课程的可能性显著更高(83%比 65%;P=0.006)。具有至少一些大学教育(优势比[OR]4.36;P=0.04)、乳腺癌诊断(OR 6.73;P=0.04)和更高水平的疼痛自我效能(OR 2.32;P=0.02)的参与者更有可能完成视频会议课程。居住离医疗中心更近(OR 0.64;P=0.07)、癌症早期(OR 3.82;P=0.07)和较少医疗合并症(OR 0.59;P=0.04)的参与者更有可能完成面对面课程。

结论

完成 PCST 课程对于改善疼痛结果很重要。应考虑增加课程完成度(例如,视频会议交付)的努力。

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