Park S H, Suh E H, Chi J G
Department of Pathology, College of Medicine, Seoul National University, Korea.
Jpn J Clin Oncol. 1988 Dec;18(4):297-302.
A histopathologic study was made on 1,095 thyroid specimens which had been removed surgically under various diagnoses at Seoul National University Hospital during the six-year period, 1976-1981. Among the 1,095 surgically removed thyroids, adenomatous goiter was the most common single disease, accounting for 43% of all cases; this was followed by papillary carcinoma and follicular adenoma. Of the malignant tumors, papillary carcinoma was the most frequent, accounting for 259 cases, 76.85% of all malignancies. Ground glass nuclei and psammoma bodies were seen in approximately 64% and 65% of the papillary carcinomas, respectively. Squamous metaplasia was, however, present in 17%. There were also 53 follicular, 13 anaplastic and seven medullary carcinomas. Of the 56 occult sclerosing carcinomas, most were detected in the backgrounds of the adenomatous goiters. Occult sclerosing carcinoma was found in 9.2% of the adenomatous goiters and in 4.3% of the follicular adenomas.
对1976年至1981年这六年期间在首尔国立大学医院因各种诊断而手术切除的1095份甲状腺标本进行了组织病理学研究。在1095例手术切除的甲状腺中，腺瘤性甲状腺肿是最常见的单一疾病，占所有病例的43%；其次是乳头状癌和滤泡性腺瘤。在恶性肿瘤中，乳头状癌最为常见，占259例，占所有恶性肿瘤的76.85%。在大约64%和65%的乳头状癌中分别可见毛玻璃样核和砂粒体。然而，17%的病例存在鳞状化生。此外，还有53例滤泡癌、13例未分化癌和7例髓样癌。在56例隐匿性硬化性癌中，大多数在腺瘤性甲状腺肿背景中被检测到。隐匿性硬化性癌在9.2%的腺瘤性甲状腺肿和4.3%的滤泡性腺瘤中被发现。
