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使用三联抗生素糊剂进行一次性根管治疗与多次根管治疗后根尖周炎坏死牙患者的术后疼痛:一项随机临床试验

Postoperative pain of patients with necrotic teeth with apical periodontitis following single visit endodontic treatment versus multiple visit endodontic treatment using triple antibiotic paste: a randomized clinical trial.

作者信息

AbdurRahman Safeya, Abdel Aziz Saied M, Gawdat Shaimaa I, AbdalSamad Ahmed M

机构信息

Department of Endodontics, Cairo University, Cairo, Egypt.

Department of Oral and Maxillofacial Radiology, Cairo University, Cairo, Egypt.

出版信息

F1000Res. 2019 Jul 26;8:1203. doi: 10.12688/f1000research.19936.1. eCollection 2019.

DOI:10.12688/f1000research.19936.1
PMID:32047601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6993827/
Abstract

A randomized clinical trial was conducted to compare the postoperative pain following endodontic treatment of necrotic teeth with apical periodontitis. Treatments were performed in multiple visits with application of triple antibiotic paste interappointment dressing or single visit without interappointment dressing. In total 44 participants were assigned randomly into two groups. Group A: multiple visit endodontic treatment with triple antibiotic paste interappointment dressing; group B: single visit endodontic treatment without interappointment dressing. Postoperative pain of participants was assessed after 24, 48, 72 hours and one week using numerical rating scale. No statistically significant difference was found in postoperative pain after 24, 48, 72 hours and one week between the two groups. Triple antibiotic paste as an interappointment dressing in multiple visits endodontic treatment was not proved to reduce the postoperative pain compared to a single visit in patients with necrotic teeth with apical periodontitis who did not have an interappointment dressing. clinicaltrials.gov, NCT02947763. Date: 28th October 2016.

摘要

进行了一项随机临床试验,以比较坏死性根尖周炎患牙根管治疗后的术后疼痛情况。治疗分多次进行,采用三联抗生素糊剂进行诊间换药,或单次就诊不进行诊间换药。总共44名参与者被随机分为两组。A组:多次就诊根管治疗并使用三联抗生素糊剂进行诊间换药;B组:单次就诊根管治疗不进行诊间换药。使用数字评分量表在术后24、48、72小时和1周时评估参与者的术后疼痛情况。两组在术后24、48、72小时和1周时的术后疼痛方面未发现统计学上的显著差异。对于患有坏死性根尖周炎且未进行诊间换药的患者,与单次就诊相比,多次就诊根管治疗中使用三联抗生素糊剂作为诊间换药并未被证明能减轻术后疼痛。clinicaltrials.gov,NCT02947763。日期:2016年10月28日。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd85/6993827/ba52902f5e69/f1000research-8-21880-g0000.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd85/6993827/ba52902f5e69/f1000research-8-21880-g0000.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd85/6993827/ba52902f5e69/f1000research-8-21880-g0000.jpg

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本文引用的文献

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Comparative evaluation of antimicrobial efficacy of triple antibiotic paste, calcium hydroxide, and a proton pump inhibitor against resistant root canal pathogens.三联抗生素糊剂、氢氧化钙和质子泵抑制剂对抗性根管病原体抗菌效果的比较评价
Eur J Dent. 2017 Jan-Mar;11(1):53-57. doi: 10.4103/ejd.ejd_159_16.
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Efficacy of Triple Antibiotic Paste, Moxifloxacin, Calcium Hydroxide And 2% Chlorhexidine Gel In Elimination of : An In vitro Study.三联抗生素糊剂、莫西沙星、氢氧化钙和2%氯己定凝胶在消除(相关因素)方面的疗效:一项体外研究
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Cochrane Database Syst Rev. 2022 Dec 13;12(12):CD005296. doi: 10.1002/14651858.CD005296.pub4.
Influence of Age and Apical Diameter on the Success of Endodontic Regeneration Procedures.
年龄和根尖直径对牙髓再生治疗成功率的影响。
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Incidence of Postoperative Pain after Single Visit and Two Visit Root Canal Therapy: A Randomized Controlled Trial.单次就诊与两次就诊根管治疗术后疼痛发生率:一项随机对照试验
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