Ascencio-Montiel Iván de Jesús
Instituto Mexicano del Seguro Social, Coordinación de Vigilancia Epidemiológica, División de Vigilancia Epidemiológica de Enfermedades No Transmisibles, Ciudad de México, México.
Rev Inst Med Trop Sao Paulo. 2020 Feb 7;62:e11. doi: 10.1590/S1678-9946202062011. eCollection 2020.
There are no studies in Mexico comparing Hepatitis C virus (HCV) epidemiology among Health Institutions. In this report, we described the deaths and hospitalizations due to HCV in the three main Health Institutions in Mexico: the Mexican Institute of Social Security, the Institute of Social Security for State Workers and the Ministry of Health, during the period 2004-2017. A secondary analysis was carried out across the country using hospital administrative death databases. Adult deaths and hospitalizations rates were calculated in reference to the total affiliated population and all-cause in-hospital mortality risk were also evaluated. There were 7,914 deaths and 9,002 hospitalizations due to HCV. Mortality and hospitalization rates of these three institutions together showed a continuous decrease over the analyzed time: the mortality rate dropped from 1.25 to 0.41 per 100,000 affiliates during 2004 and 2017, respectively (66.9% of change), and the hospitalization rate dropped from 2.19 to 0.39 per 100,000 affiliates (81.9% of change). All-cause in-hospital survival accounted for 89.6%. Older age groups and Ministry of Health hospitalizations were associated with higher all-cause in-hospital death rates. In conclusion, the mortality and hospitalizations rates found in this study reflect a decrease in the burden of HCV in Mexico.
在墨西哥，尚无关于各医疗机构间丙型肝炎病毒（HCV）流行病学的比较研究。在本报告中，我们描述了2004年至2017年期间墨西哥三个主要医疗机构（墨西哥社会保障局、州政府工作人员社会保障局和卫生部）中因HCV导致的死亡和住院情况。利用医院行政死亡数据库在全国范围内进行了二次分析。计算了成人死亡率和住院率（以总附属人口为参照），并评估了全因院内死亡风险。因HCV导致7914例死亡和9002例住院。这三个机构的死亡率和住院率在分析期内均持续下降：死亡率分别从2004年的每10万附属人口1.25例降至2017年的每10万附属人口0.41例（变化66.9%），住院率从每10万附属人口2.19例降至0.39例（变化81.9%）。全因院内生存率为89.6%。年龄较大的年龄组以及卫生部的住院患者全因院内死亡率较高。总之，本研究中发现的死亡率和住院率反映出墨西哥HCV负担有所减轻。
