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老年友善手术环境措施在普通外科急诊中的临床效果。

Clinical Effectiveness of the Elder-Friendly Approaches to the Surgical Environment Initiative in Emergency General Surgery.

机构信息

Department of Surgery, Walter C. Mackenzie Health Sciences Centre, University of Alberta, Edmonton, Alberta, Canada.

Department of Critical Care Medicine, Walter C. Mackenzie Health Sciences Centre, University of Alberta, Edmonton, Alberta, Canada.

出版信息

JAMA Surg. 2020 Apr 1;155(4):e196021. doi: 10.1001/jamasurg.2019.6021. Epub 2020 Apr 15.

Abstract

IMPORTANCE

Older adults, especially those with frailty, have a higher risk for complications and death after emergency surgery. Acute Care for the Elderly models have been successful in medical wards, but little evidence is available for patients in surgical wards.

OBJECTIVES

To develop and assess the effect of an Elder-Friendly Approaches to the Surgical Environment (EASE) model in an emergency surgical setting.

DESIGN, SETTING, AND PARTICIPANTS: This prospective, nonrandomized, controlled before-and-after study included patients 65 years or older who presented to the emergency general surgery service of 2 tertiary care hospitals in Alberta, Canada. Transfers from other medical services, patients undergoing elective surgery or with trauma, and nursing home residents were excluded. Of 6795 patients screened, a total of 684 (544 in the nonintervention group and 140 in the intervention group) were included. Data were collected from April 14, 2014, to March 28, 2017, and analyzed from November 16, 2018, through May 30, 2019.

INTERVENTIONS

Integration of a geriatric assessment team, optimization of evidence-based elder-friendly practices, promotion of patient-oriented rehabilitation, and early discharge planning.

MAIN OUTCOMES AND MEASURES

Proportion of participants experiencing a major complication or death (composite) in the hospital, Comprehensive Complication Index, length of hospital stay, and proportion of participants who required an alternative level of care on discharge. Covariate-adjusted, within-site change scores were computed, and the overall between-site, preintervention-postintervention difference-in-differences (DID) were analyzed.

RESULTS

A total of 684 patients were included in the analysis (mean [SD] age, 76.0 [7.6] years; 327 women [47.8%] and 357 men [52.2%]), of whom 139 (20.3%) were frail. At the intervention site, in-hospital major complications or death decreased by 19% (51 of 153 [33.3%] vs 19 of 140 [13.6%]; P < .001; DID P = .06), and mean (SE) Comprehensive Complication Index decreased by 12.2 (2.5) points (P < .001; DID P < .001). Median length of stay decreased by 3 days (10 [interquartile range (IQR), 6-17] days to 7 [IQR, 5-14] days; P = .001; DID P = .61), and fewer patients required an alternative level of care at discharge (61 of 153 [39.9%] vs 29 of 140 [20.7%]; P < .001; DID P = .11).

CONCLUSIONS AND RELEVANCE

To our knowledge, this is the first study to examine clinical outcomes associated with a novel elder-friendly surgical care delivery redesign. The findings suggest the clinical effectiveness of such an approach by reducing major complications or death, decreasing hospital stays, and returning patients to their home residence.

TRIAL REGISTRATION

ClinicalTrials.gov Identifier: NCT02233153.

摘要

重要性

老年人,尤其是体弱多病的老年人,在接受急诊手术后发生并发症和死亡的风险更高。急性老年护理模式在医疗病房中取得了成功,但在外科病房中,针对患者的证据有限。

目的

开发和评估老年友好型手术环境(EASE)模型在急诊外科环境中的效果。

设计、设置和参与者:这是一项前瞻性、非随机、对照前后研究,纳入了加拿大艾伯塔省 2 家三级护理医院急诊普外科服务的 65 岁及以上患者。排除从其他医疗服务转来的患者、择期手术或创伤患者以及养老院居民。在筛查的 6795 名患者中,共有 684 名患者(非干预组 544 名,干预组 140 名)入选。数据于 2014 年 4 月 14 日至 2017 年 3 月 28 日采集,并于 2018 年 11 月 16 日至 2019 年 5 月 30 日进行分析。

干预措施

老年评估团队的整合、优化基于证据的老年友好实践、促进以患者为中心的康复以及提前规划出院。

主要结果和措施

医院内发生重大并发症或死亡(复合)的参与者比例、综合并发症指数、住院时间以及需要在出院时转至其他护理水平的参与者比例。计算了经过协变量调整的、各站点内的变化评分,并分析了总体站点间、干预前-干预后的差值差异(DID)。

结果

共有 684 名患者纳入分析(平均[标准差]年龄为 76.0[7.6]岁;327 名女性[47.8%]和 357 名男性[52.2%]),其中 139 名(20.3%)为体弱。在干预站点,院内重大并发症或死亡减少了 19%(51 例[33.3%] vs 19 例[13.6%];P<0.001;DID P=0.06),综合并发症指数平均(SE)降低了 12.2(2.5)分(P<0.001;DID P<0.001)。中位住院时间缩短了 3 天(10 [四分位间距(IQR),6-17]天至 7 [IQR,5-14]天;P=0.001;DID P=0.61),出院时需要其他护理水平的患者更少(61 例[59.9%] vs 29 例[20.7%];P<0.001;DID P=0.11)。

结论和相关性

据我们所知,这是第一项研究评估与新的老年友好型手术护理提供方式相关的临床结果的研究。研究结果表明,这种方法可以减少主要并发症或死亡、缩短住院时间并使患者回到家中,从而具有临床有效性。

试验注册

ClinicalTrials.gov 标识符:NCT02233153。

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