Department of Pediatrics, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, South Korea.
J Cataract Refract Surg. 2020 Jan;46(1):45-54. doi: 10.1016/j.jcrs.2019.08.035.
To investigate the association between cataract and cotinine-verified smoking status.
Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, South Korea.
Retrospective study.
Participants were randomly selected using data collected by the Korea National Health and Nutrition Examination Survey from 2008 to 2016. Participants completed a questionnaire to self-report smoking status and a history of cataract, among other variables. To identify the relationship between cataract and smoking, a new variable was used to define smoking status, survey-cotinine-verified smoking status (SCS)-the combination of self-reported smoking status and cotinine-verified smoking status- and thus identify hidden smokers.
In total, 11 435 participants were eligible for final analysis. The study comprised 4925 men and 6510 women; the mean age was 52.86 ± 16.83 years (median: 54 years). Of 2292 SCS smokers, 382 (16.7%) were nonsmokers according to their self-report. Notably, the ratio of the cotinine-verified to self-reported smoking rate of women was greater than that of men, 1.60 and 1.06, respectively. This indicated that female hidden smokers may affect the results of studies based on self-reported questionnaires. Multivariate logistic regression analysis showed that smoking was correlated with cataract (odds ratio [OR], 1.37 [95% CI, 1.07-1.76]; OR, 1.35 [CI, 1.12-1.64]; and OR, 1.36 [CI, 1.10-1.69]) for self-reported, cotinine-verified, and SCS, respectively. No statistically significant sex difference was found.
Smoking was associated with cataract, but it did not vary by sex. Female hidden smoking must be considered when investigating the association between smoking and cataract based on self-reported questionnaires.
研究白内障与可替宁验证的吸烟状况之间的关联。
韩国成均馆大学三星医疗中心。
回顾性研究。
利用 2008 年至 2016 年韩国国家健康和营养检查调查的数据，随机选择参与者。参与者完成了一份问卷，报告吸烟状况和白内障病史等变量。为了确定白内障与吸烟之间的关系，使用了一个新的变量来定义吸烟状况，即调查可替宁验证的吸烟状况（SCS）——自我报告的吸烟状况和可替宁验证的吸烟状况的结合——从而确定隐匿性吸烟者。
共有 11435 名参与者符合最终分析标准。研究包括 4925 名男性和 6510 名女性；平均年龄为 52.86±16.83 岁（中位数：54 岁）。在 2292 名 SCS 吸烟者中，根据自我报告，有 382 名（16.7%）是非吸烟者。值得注意的是，女性的可替宁验证吸烟率与自我报告吸烟率之比大于男性，分别为 1.60 和 1.06。这表明，女性隐匿性吸烟者可能会影响基于自我报告问卷的研究结果。多变量逻辑回归分析显示，吸烟与白内障相关（比值比[OR]，1.37[95%置信区间，1.07-1.76]；OR，1.35[置信区间，1.12-1.64]；OR，1.36[置信区间，1.10-1.69]），分别用于自我报告、可替宁验证和 SCS。未发现性别差异有统计学意义。
吸烟与白内障有关，但与性别无关。基于自我报告问卷研究吸烟与白内障之间的关系时，必须考虑女性隐匿性吸烟。
