Hebert J R, Barone J
Division of Epidemiology, American Health Foundation, New York, NY 10017.
Med Hypotheses. 1988 Sep;27(1):51-4. doi: 10.1016/0306-9877(88)90083-7.
It is noted that host resistance or susceptibility factors are important in determining the probability of contracting many diseases. Though AIDS has been studied primarily in terms of exposure to disease agents, it is proposed that factors affecting susceptibility or resistance be considered. Because of its effect on cellular immunity, nutritional stress is proposed as a plausible determinant of increased risk. Specific mechanisms are discussed and a connection between diverse risk groups is proposed.
需要注意的是，宿主抵抗力或易感性因素在决定感染许多疾病的可能性方面很重要。尽管艾滋病主要是从接触病原体的角度进行研究的，但有人提出应考虑影响易感性或抵抗力的因素。由于营养应激对细胞免疫有影响，因此它被认为是风险增加的一个合理决定因素。文中讨论了具体机制，并提出了不同风险群体之间的联系。
