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结直肠癌研究：基础、临床前及临床方法

Colorectal Cancer Research: Basic, Preclinical, and Clinical Approaches.

作者信息

Beaulieu Jean-François

机构信息

Laboratory of Intestinal Physiopathology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.

Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.

出版信息

Cancers (Basel). 2020 Feb 11;12(2):416. doi: 10.3390/cancers12020416.

DOI:10.3390/cancers12020416
PMID:32053872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7072293/
Abstract

Colorectal cancer remains one of the deadliest cancers worldwide. It has become evident that further efforts in colorectal cancer research are required, from providing a better understanding of the cellular and molecular mechanisms leading to colorectal neoplasm initiation and progression from adenoma to metastasis, to generating reliable non-invasive detection tests for identifying lesions at early stages, as well as refining the current therapeutic and personalized approaches and developing new ones. The aim of this Special Issue is to cover all aspects of colorectal cancer research, including basic, preclinical, and clinical approaches.[...].

摘要

结直肠癌仍然是全球最致命的癌症之一。很明显，结直肠癌研究需要进一步努力，从更好地理解导致结直肠肿瘤发生以及从腺瘤发展到转移的细胞和分子机制，到开发可靠的非侵入性检测方法以早期识别病变，以及完善当前的治疗和个性化方法并开发新方法。本期特刊的目的是涵盖结直肠癌研究的各个方面，包括基础、临床前和临床方法。[...]

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Colorectal Cancer Research: Basic, Preclinical, and Clinical Approaches.结直肠癌研究：基础、临床前及临床方法
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引用本文的文献

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Immunotherapy in Metastatic Colorectal Cancer: Could the Latest Developments Hold the Key to Improving Patient Survival?转移性结直肠癌的免疫治疗：最新进展能否成为提高患者生存率的关键？
Cancers (Basel). 2020 Apr 6;12(4):889. doi: 10.3390/cancers12040889.

本文引用的文献

1
Integrin α6β4 in Colorectal Cancer: Expression, Regulation, Functional Alterations and Use as a Biomarker.整合素α6β4在结直肠癌中的表达、调控、功能改变及其作为生物标志物的应用
Cancers (Basel). 2019 Dec 21;12(1):41. doi: 10.3390/cancers12010041.
2
Crosstalk between SHH and FGFR Signaling Pathways Controls Tissue Invasion in Medulloblastoma.SHH与FGFR信号通路之间的相互作用调控髓母细胞瘤中的组织侵袭
Cancers (Basel). 2019 Dec 10;11(12):1985. doi: 10.3390/cancers11121985.
3
Integrated Biobanking and Tumor Model Establishment of Human Colorectal Carcinoma Provides Excellent Tools for Preclinical Research.人结直肠癌的综合生物样本库建立与肿瘤模型构建为临床前研究提供了优良工具。
Cancers (Basel). 2019 Oct 9;11(10):1520. doi: 10.3390/cancers11101520.
4
How to Deal with Second Line Dilemma in Metastatic Colorectal Cancer? A Systematic Review and Meta-Analysis.如何应对转移性结直肠癌的二线治疗困境？一项系统评价与Meta分析
Cancers (Basel). 2019 Aug 15;11(8):1189. doi: 10.3390/cancers11081189.
5
Maintenance BEZ235 Treatment Prolongs the Therapeutic Effect of the Combination of BEZ235 and Radiotherapy for Colorectal Cancer.维持性BEZ235治疗可延长BEZ235与放疗联合治疗结直肠癌的疗效。
Cancers (Basel). 2019 Aug 19;11(8):1204. doi: 10.3390/cancers11081204.
6
Hepatic Resection Following Selective Internal Radiation Therapy for Colorectal Cancer Metastases in the FOXFIRE Clinical Trial: Clinical Outcomes and Distribution of Microspheres.FOXFIRE临床试验中针对结直肠癌肝转移进行选择性内放射治疗后的肝切除术：临床结果及微球分布
Cancers (Basel). 2019 Aug 12;11(8):1155. doi: 10.3390/cancers11081155.
7
Genetic Aberration Analysis in Thai Colorectal Adenoma and Early-Stage Adenocarcinoma Patients by Whole-Exome Sequencing.通过全外显子组测序对泰国结直肠腺瘤和早期腺癌患者进行基因畸变分析。
Cancers (Basel). 2019 Jul 12;11(7):977. doi: 10.3390/cancers11070977.
8
Flavopereirine Suppresses the Growth of Colorectal Cancer Cells through P53 Signaling Dependence.黄肉楠碱通过依赖P53信号通路抑制结肠癌细胞生长。
Cancers (Basel). 2019 Jul 22;11(7):1034. doi: 10.3390/cancers11071034.
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The Molecular Hallmarks of the Serrated Pathway in Colorectal Cancer.结直肠癌锯齿状通路的分子特征
Cancers (Basel). 2019 Jul 20;11(7):1017. doi: 10.3390/cancers11071017.
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Cancers (Basel). 2019 Jul 3;11(7):931. doi: 10.3390/cancers11070931.