Department of Physiology, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Department of Pediatrics, Diabetology and Endocrinology, Gdansk Medical University, 80-210 Gdansk, Poland.
Nutrients. 2020 Feb 11;12(2):454. doi: 10.3390/nu12020454.
The main purpose of this study was to investigate the differences in glycaemic reaction in response to various physical activities in 20 young boys (14.4 ± 1.6 years) with type 1 diabetes mellitus (T1DM) and with either vitamin D deficiency or with suboptimal levels of vitamin D. Participants were divided into two groups (deficiency group-DG, = 10; suboptimal group-SG, = 10) according to their vitamin D levels. All patients performed aerobic and mixed (aerobic-anaerobic) physical efforts. During the exercise, the respiratory responses and glucose levels were monitored. Biochemical blood analyses were performed before each physical effort. The oxygen consumption was not significantly lower in SG during both aerobic and mixed effort (4.0% and 5.6%, respectively). The glycated haemoglobin (HbA1c) level was higher by 6.1% and the total daily dose of insulin (DDI) was higher by 18.4% in the DG. The differences were not statistically significant. Patients with lower vitamin D levels demonstrated an insignificantly higher glycaemic variability during days with both aerobic and mixed exercises. An appropriate vitamin D concentration in T1DM patients' blood may constitute a prophylactic factor for hyperglycaemia during anaerobic training and hypoglycaemia during aerobic training.
本研究的主要目的是调查 20 名 1 型糖尿病（T1DM）年轻男性（14.4 ± 1.6 岁）在不同体力活动下血糖反应的差异，这些男性中有的存在维生素 D 缺乏，有的则存在维生素 D 水平不足。根据维生素 D 水平，参与者被分为两组（缺乏组-DG，n = 10；亚组-SG，n = 10）。所有患者均进行有氧运动和混合（有氧-无氧）体力活动。运动过程中监测呼吸反应和血糖水平。每次体力活动前均进行生化血液分析。在有氧运动和混合运动中，SG 的耗氧量均无显著降低（分别为 4.0%和 5.6%）。DG 的糖化血红蛋白（HbA1c）水平升高 6.1%，胰岛素日总剂量（DDI）升高 18.4%。但差异无统计学意义。维生素 D 水平较低的患者在进行有氧运动和混合运动的日子里，血糖变异性略高。T1DM 患者血液中适当的维生素 D 浓度可能是预防无氧训练时高血糖和有氧运动时低血糖的一个因素。
