Aqsa Anum, Sharma Dikshya, Chalhoub Michel
Staten Island University Hospital, 522A seaview avenue, Staten Island, United States.
Respir Med Case Rep. 2020 Feb 1;29:101012. doi: 10.1016/j.rmcr.2020.101012. eCollection 2020.
Tumor necrosis factor inhibitors have been implicated in many pulmonary complications. Before starting these class of drugs latent infection as tuberculosis and preexisting lung disease should be excluded. These agents have been linked to pulmonary nodules, pneumonitis, fibrosis, autoimmune reactions and infection. We report a case of adalimumab induced organizing pneumonia in an old gentleman who was started on the drug for his uncontrolled Psoriasis.
肿瘤坏死因子抑制剂与许多肺部并发症有关。在开始使用这类药物之前,应排除潜伏感染如结核病和既往存在的肺部疾病。这些药物与肺结节、肺炎、纤维化、自身免疫反应及感染有关。我们报告一例在一位老年男性中由阿达木单抗诱发的机化性肺炎,该患者因银屑病控制不佳而开始使用该药。