Department of Rheumatology, Ome Municipal General Hospital, 4-16-5 Higashi-Ome, Ome, Tokyo 198-0042, Japan.
Mod Rheumatol. 2010 Oct;20(5):518-21. doi: 10.1007/s10165-010-0308-4. Epub 2010 May 14.
A 64-year-old woman with rheumatoid arthritis (RA) began to complain of recurrent non-productive cough 5 months after starting adalimumab. The chest radiograph and high-resolution computed tomographic findings revealed diffuse ground-glass attenuation. Her clinical course suggested that interstitial pneumonia (IP) may have been induced by adalimumab, and she was successfully treated with a medium dose of corticosteroid. This case indicates that adalimumab-associated IP should be considered if a RA patient develops non-productive cough following adalimumab therapy.
一位 64 岁的类风湿关节炎（RA）女性患者，在开始使用阿达木单抗治疗后 5 个月开始反复出现无痰干咳。胸部 X 线片和高分辨率计算机断层扫描（HRCT）结果显示弥漫性磨玻璃影。她的临床过程提示可能是阿达木单抗引起的间质性肺炎（IP），经中剂量皮质类固醇治疗后病情缓解。该病例表明，如果 RA 患者在阿达木单抗治疗后出现无痰干咳，应考虑阿达木单抗相关间质性肺炎。
