Egan Jillian, Vranic Gayle, Ghasemian Seyed Reza
MedStar Georgetown University Hospital, USA.
Urol Case Rep. 2019 Oct 10;30:101042. doi: 10.1016/j.eucr.2019.101042. eCollection 2020 May.
Adenovirus is a rare cause of hemorrhagic cystitis in the transplant population. We present a case of a forty-one-year-old man with end-stage renal disease who underwent living unrelated donor kidney transplant in 2016. In 2018 he presented with acute onset gross hematuria and dysuria, with serologic testing and immunohistochemical stains of biopsy specimens positive for adenovirus. He was treated with reduction in immunosuppression, cystoscopy with evacuation of clots, and alum bladder irrigation. His hematuria resolved almost immediately with no recurrence to date. This case demonstrates the efficacy and safety of alum irrigation in patients with adenovirus hemorrhagic cystitis.
腺病毒是移植人群出血性膀胱炎的罕见病因。我们报告一例41岁终末期肾病男性病例，该患者于2016年接受了非亲属活体供肾移植。2018年，他出现急性肉眼血尿和排尿困难，血清学检测及活检标本免疫组化染色显示腺病毒阳性。他接受了免疫抑制减量、膀胱镜下血凝块清除及明矾膀胱灌注治疗。他的血尿几乎立即消失，至今未复发。该病例证明了明矾灌注治疗腺病毒出血性膀胱炎患者的有效性和安全性。
