Duong Minh C, Nguyen Van T T, Otsu Satoko, McLaws Mary-Louise
School of Public Health and Community Medicine University of New South Wales Sydney New South Wales Australia.
World Health Organization Hanoi Vietnam.
JGH Open. 2019 Jun 17;4(1):29-38. doi: 10.1002/jgh3.12199. eCollection 2020 Feb.
Chronic hemodialysis patients are at high risk of contracting hepatitis B (HBV) and C (HCV) virus infections. In Vietnam, the seroprevalence of HBV and HCV infections is approximately 10 and 4%, respectively. Although the chronic hemodialysis population is increasing, relatively little epidemiology is available for HBV and HCV infections in this population. To address this, we reviewed the current literature on the magnitude of these infections in the hemodialysis population in Vietnam.
Four databases were used to search for publications containing the prevalence of HBV and/or HCV infections in hemodialysis patients in Vietnam. Grey literature search was utilized to identify local publications. Prevalence and 95% confidence interval were used or calculated, and a meta-analysis was conducted on HBV and HCV prevalence for comparison.
Sixteen studies were included in the review. The search identified knowledge gaps in the current literature. Available data show that HBV and HCV infections remain prevalent in the hemodialysis population. HBV prevalence is not different between the north and the south of Vietnam. The pattern of HCV prevalence is different, with recent reports of lower prevalence in the south than in the north, while HCV prevalence varies between hemodialysis units in the same regions.
A national prevalence survey of hemodialysis patients would improve the reliability and generalizability of the findings. However, the review confirmed that both HBV and HCV were prevalent in hemodialysis patients. The findings support a reinforcement of infection prevention to minimize the risk of HBV and HCV transmission in hemodialysis facilities.
慢性血液透析患者感染乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）的风险很高。在越南，HBV和HCV感染的血清流行率分别约为10%和4%。尽管慢性血液透析人群在不断增加，但关于该人群中HBV和HCV感染的流行病学资料相对较少。为解决这一问题，我们回顾了越南血液透析人群中这些感染情况的现有文献。
使用四个数据库搜索包含越南血液透析患者中HBV和/或HCV感染患病率的出版物。利用灰色文献搜索来识别当地出版物。使用或计算患病率及95%置信区间，并对HBV和HCV患病率进行荟萃分析以作比较。
该综述纳入了16项研究。搜索发现了当前文献中的知识空白。现有数据表明，HBV和HCV感染在血液透析人群中仍然普遍存在。越南南北部的HBV患病率没有差异。HCV患病率模式不同，最近有报道称南部的患病率低于北部，而同一地区不同血液透析单位的HCV患病率也有所不同。
对血液透析患者进行全国患病率调查将提高研究结果的可靠性和普遍性。然而，该综述证实HBV和HCV在血液透析患者中均普遍存在。这些发现支持加强感染预防措施，以将血液透析设施中HBV和HCV传播的风险降至最低。
