Ulusoy Ersin Kasım, Bolattürk Ömer Faruk
Neurology Department, Kayseri Training and Research Hospital, Şeker Mahallesi, Molu Yolu/Kocasinan, 38010, Kayseri, Turkey.
Neurol Sci. 2020 Jul;41(7):1829-1835. doi: 10.1007/s10072-020-04286-9. Epub 2020 Feb 13.
The greater occipital nerve block (GONB) with local anesthetics is an effective treatment for chronic migraine (CM). In this study, it was aimed to demonstrate the change in quality of life, depression, anxiety, and sleep disturbance scores before and after treatment in CM patients who underwent GONB and the effectiveness of treatment.
The study included 84 patients diagnosed as CM according to the International Classification of Headache Disorders III beta version diagnostic criteria. The 24-Hour Migraine Quality of Life Questionnaire (MQoLQ), Migraine Disability Assessment Scale (MIDAS), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), Pittsburgh Sleep Quality Index (PSQI), Headache Impact Test (HIT), and Visual Analog Scale (VAS) were applied on patients before GONB treatment and at posttreatment months 1 and 3.
MQoLQ scores, which measured the daily quality of life, were 38 [3-66] before GONB treatment, and 64 [38-88] in the first month and 72 [40-86] in the third month after treatment. In addition, this increase was statistically significant (p < 0.001). Furthermore, we found a statistically significant decrease in disability, depression, anxiety, and sleep disturbance scores after treatment (p < 0.05).
In this study, we observed a prominent improvement in quality of life and disability rates of CM patients treated with GONB compared to pretreatment. We also demonstrated that the treatment was effective in comorbid depression, anxiety, and sleep disturbance scores.
使用局部麻醉剂进行枕大神经阻滞（GONB）是治疗慢性偏头痛（CM）的有效方法。本研究旨在证明接受GONB治疗的CM患者治疗前后生活质量、抑郁、焦虑和睡眠障碍评分的变化以及治疗效果。
本研究纳入了84例根据《国际头痛疾病分类》第三版β版诊断标准确诊为CM的患者。在GONB治疗前以及治疗后第1个月和第3个月，对患者应用24小时偏头痛生活质量问卷（MQoLQ）、偏头痛残疾评估量表（MIDAS）、贝克焦虑量表（BAI）、贝克抑郁量表（BDI）、匹兹堡睡眠质量指数（PSQI）、头痛影响测试（HIT）和视觉模拟量表（VAS）。
衡量日常生活质量的MQoLQ评分在GONB治疗前为38[3-66]，治疗后第1个月为64[38-88]，第3个月为72[40-86]。此外，这种增加具有统计学意义（p<0.001）。此外，我们发现治疗后残疾、抑郁、焦虑和睡眠障碍评分有统计学意义的下降（p<0.05）。
在本研究中，我们观察到与治疗前相比，接受GONB治疗的CM患者的生活质量和残疾率有显著改善。我们还证明该治疗对合并的抑郁、焦虑和睡眠障碍评分有效。
