Guner Derya, Eyigor Can
Pain Department, Tepecik Training and Research Hospital, Izmir University of Health Sciences, Izmir, Turkey.
Pain Department, Ege University Faculty of Medicine, Izmir, Turkey.
Acta Neurol Belg. 2023 Feb;123(1):191-198. doi: 10.1007/s13760-022-01972-7. Epub 2022 Jun 2.
Ultrasound (US) guided pulsed radiofrequency (PRF) therapy can be used on the greater occipital nerve (GON) in patients with chronic migraine (CM) who are unresponsive to conservative treatments. We aimed to demonstrate the change in pain intensity, duration of migraine episodes, frequency of attacks, migraine disability, depression, and sleep disturbance scores before and after treatment in patients with CM who underwent US-guided GON PRF and the effectiveness of treatment.
According to the International Classification of Headache Disorders III beta version diagnostic criteria, 25 of 43 patients with CM whom treated with GON PRF were included in the study. The Migraine Disability Assessment Scale (MIDAS), Beck Depression Inventory (BDI), Pittsburgh Sleep Quality Index (PSQI), and a visual analog scale (VAS) were used on patients before GON PRF treatment and at post treatment months 1 and 3.
The median duration and number of migraine episodes in the post-interventional 1st month and 3rd month were significantly shorter and fewer compared with the pre-intervention period (p < 0.001). In the comparison with the pre-intervention values, all of the scoring concepts, namely the MIDAS, VAS, BDI, and PSQI, revealed a significant drop in the postintervention 1st and 3rd month (p < 0.001).
In this study, we observed that US-guided GON PRF therapy applied at the proximal (C2) level was a safe and effective treatment option. With GON PRF, we observed a decrease in pain intensity, pain frequency, and duration of episodes, and an improvement in depression symptoms, migraine disability, and sleep disorder scores accompanying chronic migraine.
对于对保守治疗无反应的慢性偏头痛(CM)患者,超声(US)引导下的脉冲射频(PRF)治疗可用于枕大神经(GON)。我们旨在证明接受US引导下GON PRF治疗的CM患者治疗前后疼痛强度、偏头痛发作持续时间、发作频率、偏头痛残疾、抑郁和睡眠障碍评分的变化以及治疗效果。
根据国际头痛疾病分类第三版β版诊断标准,43例接受GON PRF治疗的CM患者中有25例纳入研究。在GON PRF治疗前以及治疗后第1个月和第3个月,对患者使用偏头痛残疾评估量表(MIDAS)、贝克抑郁量表(BDI)、匹兹堡睡眠质量指数(PSQI)和视觉模拟量表(VAS)。
与干预前相比,干预后第1个月和第3个月偏头痛发作的中位持续时间和发作次数显著缩短和减少(p < 0.001)。与干预前值相比,所有评分指标,即MIDAS、VAS、BDI和PSQI,在干预后第1个月和第3个月均显著下降(p < 0.001)。
在本研究中,我们观察到在近端(C2)水平进行的US引导下GON PRF治疗是一种安全有效的治疗选择。通过GON PRF,我们观察到疼痛强度、疼痛频率和发作持续时间降低,以及伴随慢性偏头痛的抑郁症状、偏头痛残疾和睡眠障碍评分得到改善。