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肺腺癌垂体转移:病例报告及文献综述

Pituitary metastasis of lung adenocarcinoma: Case report and literature review.

作者信息

Alhashem Aminah, Taha Mahmoud, Almomen Ali

机构信息

Imam Abdulrahman Bin Faisal University, Saudi Arabia.

Department of Neurosurgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia.

出版信息

Int J Surg Case Rep. 2020;67:98-101. doi: 10.1016/j.ijscr.2020.01.013. Epub 2020 Jan 23.

Abstract

INTRODUCTION

Pituitary metastasis is rare, and it is the least common site of intracranial metastases. It is mostly asymptomatic but can present with diabetes insipidus, headache, ophthalmoplegia, visual disturbance and anterior pituitary dysfunction and in majority of cases patients known to have a primary malignancy.

CASE PRESENTATION

This study presents a 54-year-old male presented with a few months history of headache and drooping of both eyelids and after proper investigations and endoscopic resection of the sellar mass the diagnosis was confirmed to be pituitary metastasis of lung adenocarcinoma.

CONCLUSION

Diagnosis and management of pituitary metastases are complex and depend on many factors. Endoscopic surgical resection and debulking alleviates symptoms and provides the definitive diagnosis which has great importance in cases with clinical presentation that does not strongly point to pituitary metastasis to avoid unnecessary radiotherapy and chemotherapy when possible.

摘要

引言

垂体转移瘤较为罕见,是颅内转移最不常见的部位。多数情况下无症状,但可出现尿崩症、头痛、眼肌麻痹、视力障碍及垂体前叶功能障碍,且大多数患者已知患有原发性恶性肿瘤。

病例报告

本研究报告了一名54岁男性,有几个月的头痛和双侧眼睑下垂病史,经过适当检查及对鞍区肿块进行内镜切除后,确诊为肺腺癌垂体转移。

结论

垂体转移瘤的诊断和治疗较为复杂,取决于多种因素。内镜手术切除及减瘤可缓解症状并提供明确诊断,这对于临床表现不强烈提示垂体转移的病例非常重要,以便尽可能避免不必要的放疗和化疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/083d/7016037/d65a80df7a36/gr1.jpg

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