Hitu Liviu, Cainap Calin, Apostu Dragos, Gabora Katalin, Bonci Eduard-Alexandru, Badan Marius, Mester Alexandru, Piciu Andra
Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Department of Medical Oncology, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Diagnostics (Basel). 2020 Feb 12;10(2):100. doi: 10.3390/diagnostics10020100.
Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy and is characterized by slow growth and an indolent biological behavior. Papillary thyroid microcarcinoma is the PTC with the maximum size of the tumor <1cm, considered the most indolent form of thyroid cancer. PTC is usually metastasizes in cervical lymph nodes, lungs and bones and, less commonly, in brain or liver. Skeletal muscle metastases from PTC are extremely rare, a retrospective review of the literature revealed only 13 case reports. Among them, six cases are solitary skeletal muscle metastases, and seven are multiple metastases, most of them being associated with lung lesions. It seems that PTC is prone to metastasizing to the erector spinae and thigh muscles groups with unique cases located in trapezoid, biceps, deltoid, gastrocnemius and rectus abdominis muscles. Although extremely rare, one must bear in mind the fact that muscle metastasis from PTC is possible, and that is the reason we would like to discuss the existing clinical cases and to add a unique case of solitary skeletal muscle metastasis from papillary microcarcinoma.
甲状腺乳头状癌（PTC）是最常见的甲状腺恶性肿瘤类型，其特点是生长缓慢且生物学行为惰性。甲状腺微小乳头状癌是肿瘤最大径＜1cm的PTC，被认为是甲状腺癌最惰性的形式。PTC通常转移至颈部淋巴结、肺和骨骼，较少转移至脑或肝脏。PTC发生骨骼肌转移极为罕见，一项文献回顾显示仅有13例病例报告。其中，6例为孤立性骨骼肌转移，7例为多发性转移，大多数伴有肺部病变。似乎PTC易于转移至竖脊肌和大腿肌群，也有独特病例发生于斜方肌、肱二头肌、三角肌、腓肠肌和腹直肌。尽管极为罕见，但必须牢记PTC发生肌肉转移是有可能的，这就是我们想要讨论现有临床病例并补充一例乳头状微小癌孤立性骨骼肌转移独特病例的原因。
