利用克鲁日-纳波卡市伊昂·基里库塔肿瘤研究所的数据库，对甲状腺癌进行了40多年的研究。

Investigation of thyroid carcinoma over 40 years, using the database of the Ion Chiricuta Institute of Oncology Cluj-Napoca.

作者信息

Piciu Doina, Irimie Alexandru, Piciu Andra

机构信息

Ion Chiricuta Institute of Oncology, Cluj-Napoca, Romania.

出版信息

J BUON. 2014 Apr-Jun;19(2):524-9.

PMID:24965416

Abstract

PURPOSE

The purpose of this retrospective study was to analyse incidence trends for thyroid cancer (TC) treated at the Ion Chiricuta Institute of Oncology (IOCN), Romania.

METHODS

Between 1970 and 2009, 2838 patients at our institute were diagnosed with TC, treated and followed up. We analysed epidemiological data, distribution by age groups,sex, histopathological diagnosis, treatments and 5- and 10-year overall survival rates.

RESULTS

TC increased 10-fold in the last decade. Patients' mean age ± standard deviation (SD) was 45.6 (±27.8) years. Although women represented 88.8% and men 11.2% of these patients, men's 5-year overall survival rate (89.7%) was lower - but not significantly - than that of women's (97.9%) (p=0.435). Patients aged 46 years and older had the lowest 5- and 10-year overall survival rates (94.9 and 87.8%, respectively).

CONCLUSION

Aggressive histology, older age and male gender significantly influenced survival rates. The high incidence of TC underlines the necessity of having a national/ regional TC registry to improve our epidemiological data.

摘要

目的

本回顾性研究旨在分析罗马尼亚伊翁·基里库塔肿瘤研究所（IOCN）治疗的甲状腺癌（TC）的发病率趋势。

方法

1970年至2009年间，我院2838例患者被诊断为TC，并接受治疗和随访。我们分析了流行病学数据、按年龄组、性别、组织病理学诊断、治疗方法以及5年和10年总生存率的分布情况。

结果

在过去十年中，TC发病率增长了10倍。患者的平均年龄±标准差（SD）为45.6（±27.8）岁。尽管女性占这些患者的88.8%，男性占11.2%，但男性的5年总生存率（89.7%）低于女性（97.9%），但差异不显著（p = 0.435）。46岁及以上患者的5年和10年总生存率最低（分别为94.9%和87.8%）。