Delarue T, Masson C, Maheo A, Foissey A
Service de Gynécologie-Obstétrique, Centre Hospitalier, Vitré.
Rev Fr Gynecol Obstet. 1988 Nov;83(11):679-86.
Based on a personal series of 54 cases of endo-uterine haemorrhage with normal endometrium, the authors show that lesions of the myometrium which may result in haemorrhages, consist mainly of interstitial or submucous myomas and adenomyosis, i.e. lesions on which medical treatments are ineffective. Ultrasonography, but mainly clinical data and hysterography very often demonstrate the lesions and are sufficient to indicate a hysterectomy or a myomectomy. The problem is more difficult when the clinical, ultrasonographic and hysterographic work-up is negative or barely evocative. In these cases, after ruling out certain functional haemorrhages or a haemorrhagic disease, it is useful to take an histological sample of the endometrium either by curettage or biopsy, on an ambulatory basis (using Inocurette for instance). If this examination is normal, hysterectomy is indicated, because, in their experience, there are such lesions of the myometrium, that recurrence of the haemorrhages is inevitable.
基于作者个人收集的54例子宫内膜正常的子宫内出血病例,研究表明,可能导致出血的子宫肌层病变主要包括间质性或黏膜下肌瘤以及子宫腺肌病,即药物治疗无效的病变。超声检查,但主要是临床资料和子宫输卵管造影术常常能显示这些病变,并且足以表明需要进行子宫切除术或肌瘤切除术。当临床、超声和子宫输卵管造影检查结果为阴性或仅有微弱提示时,问题就更加棘手。在这些情况下,在排除某些功能性出血或出血性疾病后,通过刮宫或活检在门诊获取子宫内膜组织样本(例如使用Inocurette)是有用的。如果该检查结果正常,则表明需要进行子宫切除术,因为根据他们的经验,存在这样的子宫肌层病变,出血复发是不可避免的。