加泰罗尼亚医护人员破伤风和白喉的免疫状况。
The immune status against tetanus and diphtheria in healthcare workers in Catalonia.
机构信息
Servei de Medicina Preventiva, Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, Barcelona, Spain.
Servei de Prevenció, Institut d'Assistència Sanitària, Salt, Girona, Spain.
出版信息
Vaccine. 2020 Mar 10;38(12):2646-2650. doi: 10.1016/j.vaccine.2020.01.076. Epub 2020 Feb 13.
The objective was to investigate the immune status against tetanus and diphtheria of healthcare workers in Catalonia. A cross-sectional multicentre study was conducted in seven health centres. Blood samples were obtained, and demographic and clinical variables collected. 509 health workers were included. The prevalence of protective antibodies against tetanus was 94.7% (95% CI: 92.3-96.4) overall and 85.1% (95% CI: 74.5-92.0) in workers aged ≥55 years. The prevalence of protective antibodies against diphtheria was 68.6% (95% CI: 64.3-72.5%) overall and 29.7% (95% CI: 19.9-41.6) in workers aged ≥55 years. Protection against tetanus in healthcare workers is high, but should be improved in workers aged ≥55 years. Protection against diphtheria has improved in healthcare workers over the past decade (68.6% vs 46.5%) but should be improved in all ages, especially in workers aged ≥55 years.
目的在于调查加泰罗尼亚医护人员针对破伤风和白喉的免疫状况。在七个医疗中心进行了一项横断面多中心研究。采集血样并收集人口统计学和临床变量。共纳入 509 名医护人员。总体而言，保护性破伤风抗体的流行率为 94.7%（95%CI：92.3-96.4），≥55 岁的工作人员中为 85.1%（95%CI：74.5-92.0）。总体而言，保护性白喉抗体的流行率为 68.6%（95%CI：64.3-72.5%），≥55 岁的工作人员中为 29.7%（95%CI：19.9-41.6）。医护人员对破伤风的保护作用较高，但≥55 岁的工作人员应加以改善。在过去十年中，医护人员对白喉的保护作用有所提高（68.6%对 46.5%），但应在所有年龄段，尤其是≥55 岁的工作人员中加以提高。
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