Pasha Hamdan, Siddiqui Moghira Iqbal, Wasif Muhammad
Department of Otolaryngology and Head and Neck Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Department of Otolaryngology, Aga Khan University Hospital, Karachi, Pakistan.
J Pak Med Assoc. 2020 Feb;70(2):354-356. doi: 10.5455/JPMA.13110.
Castleman disease is a rare lymphoproliferative disorder with two distinctive presentations, namely Unicentric disease and Multicentric disease. Unicentric disease occurs as a solitary enlarged mass in the mediastinum and is rarely found in the head and the neck, whereas, Multicentric disease appears as a systemic disease with peripheral lymphadenopathy. Here we discuss an unusual case with characteristic clinical, radiologic and histologic findings of a 22-year-old male with Unicentric disease demonstrating a slow growing neck mass often times misdiagnosed as a lymphoma.
卡斯特曼病是一种罕见的淋巴增生性疾病,有两种不同的表现形式,即单中心型疾病和多中心型疾病。单中心型疾病表现为纵隔内单个肿大的肿块,很少见于头颈部;而多中心型疾病则表现为伴有外周淋巴结病的全身性疾病。在此,我们讨论一例不寻常的病例,该病例为一名22岁患有单中心型疾病的男性,具有特征性的临床、放射学和组织学表现,其颈部肿块生长缓慢,常被误诊为淋巴瘤。