Park Soo-Hyun, Jung Su-Jin, Choi Eun-Kyung, Ha Ki-Chan, Baek Hyang-Im, Park Yu-Kyung, Han Kap-Hoon, Jeong Soon-Yeon, Oh Jung-Hee, Cha Youn-Soo, Park Byung-Hyun, Chae Soo-Wan
1Clinical Trial Center for Functional Foods, Chonbuk National University Hospital, Jeonju-si, Republic of Korea.
2Department of Food Science and Human Nutrition, Chonbuk National University, Jeonju-si, Republic of Korea.
Food Sci Biotechnol. 2019 Oct 11;29(2):265-273. doi: 10.1007/s10068-019-00649-x. eCollection 2020 Feb.
Steamed ginger ethanolic extract (SGE) is a product with a high 6-shogaol contents and is thought to be more potent than other ginger products. We conducted a 12-week, randomized, double-blind, placebo-controlled clinical trial to determine the effects of SGE on weight and body fat loss. Eighty healthy obese participants were recruited and randomly divided into the SGE and placebo groups. The outcome measures comprised indicators of efficacy (body weight, body mass index, body composition, and blood markers) and safety. Following the supplementation period, mean body weight, body mass index, and body fat level were significantly lower in the SGE group than in the placebo group. No clinically significant changes were observed for any safety parameter. These results suggest that SGE is a potent anti-obesity agent that does not cause significant side effects. Therefore, SGE supplementation combined with lifestyle modification could be effective in the management of body weight and fat mass.
蒸制生姜乙醇提取物(SGE)是一种6-姜辣素含量高的产品,被认为比其他生姜产品更具效力。我们进行了一项为期12周的随机、双盲、安慰剂对照临床试验,以确定SGE对体重和体脂减少的影响。招募了80名健康肥胖参与者,并将他们随机分为SGE组和安慰剂组。结果指标包括疗效指标(体重、体重指数、身体成分和血液指标)和安全性指标。在补充期结束后,SGE组的平均体重、体重指数和体脂水平显著低于安慰剂组。未观察到任何安全参数有临床显著变化。这些结果表明,SGE是一种有效的抗肥胖剂,不会引起显著的副作用。因此,补充SGE并结合生活方式的改变可能对体重和体脂管理有效。