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The antioxidant activity of steamed ginger and its protective effects on obesity induced by high-fat diet in C57BL/6J mice.蒸制生姜的抗氧化活性及其对C57BL/6J小鼠高脂饮食诱导肥胖的保护作用。
Nutr Res Pract. 2018 Dec;12(6):503-511. doi: 10.4162/nrp.2018.12.6.503. Epub 2018 Nov 30.
2
Heat-induced conversion of gingerols to shogaols in ginger as affected by heat type (dry or moist heat), sample type (fresh or dried), temperature and time.受热类型(干热或湿热)、样品类型(新鲜或干燥)、温度和时间影响,生姜中姜辣素受热转化为姜烯酚的过程。
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Obesity and cardiovascular risk: a call for action from the European Society of Hypertension Working Group of Obesity, Diabetes and the High-risk Patient and European Association for the Study of Obesity: part B: obesity-induced cardiovascular disease, early prevention strategies and future research directions.肥胖与心血管风险:欧洲高血压学会肥胖、糖尿病和高危患者工作组及欧洲肥胖研究协会的行动呼吁:B 部分:肥胖导致的心血管疾病、早期预防策略和未来研究方向。
J Hypertens. 2018 Jul;36(7):1441-1455. doi: 10.1097/HJH.0000000000001731.
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Comparison of Inhibitory Capacities of 6-, 8- and 10-Gingerols/Shogaols on the Canonical NLRP3 Inflammasome-Mediated IL-1β Secretion.6-、8-和 10-姜酚/姜酮对经典 NLRP3 炎性小体介导的 IL-1β 分泌的抑制能力比较。
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Occurrence, biological activity and metabolism of 6-shogaol.6-姜烯酚的发生、生物活性和代谢。
Food Funct. 2018 Mar 1;9(3):1310-1327. doi: 10.1039/c7fo01354j. Epub 2018 Feb 8.
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The effects of ginger intake on weight loss and metabolic profiles among overweight and obese subjects: A systematic review and meta-analysis of randomized controlled trials.摄入生姜对超重和肥胖受试者体重减轻和代谢指标的影响:系统评价和随机对照试验的荟萃分析。
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Body mass index, abdominal adiposity, weight gain and risk of developing hypertension: a systematic review and dose-response meta-analysis of more than 2.3 million participants.体重指数、腹部肥胖、体重增加与高血压发病风险:超过 230 万参与者的系统评价和剂量-反应荟萃分析。
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Neuroprotective effect of licochalcone A against oxygen-glucose deprivation/reperfusion in rat primary cortical neurons by attenuating oxidative stress injury and inflammatory response via the SIRT1/Nrf2 pathway.甘草查尔酮 A 通过 SIRT1/Nrf2 通路减轻氧化应激损伤和炎症反应对大鼠原代皮质神经元氧葡萄糖剥夺/再灌注的神经保护作用。
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蒸制生姜乙醇提取物对体重和体脂减少的影响:一项随机、双盲、安慰剂对照临床试验。

The effects of steamed ginger ethanolic extract on weight and body fat loss: a randomized, double-blind, placebo-controlled clinical trial.

作者信息

Park Soo-Hyun, Jung Su-Jin, Choi Eun-Kyung, Ha Ki-Chan, Baek Hyang-Im, Park Yu-Kyung, Han Kap-Hoon, Jeong Soon-Yeon, Oh Jung-Hee, Cha Youn-Soo, Park Byung-Hyun, Chae Soo-Wan

机构信息

1Clinical Trial Center for Functional Foods, Chonbuk National University Hospital, Jeonju-si, Republic of Korea.

2Department of Food Science and Human Nutrition, Chonbuk National University, Jeonju-si, Republic of Korea.

出版信息

Food Sci Biotechnol. 2019 Oct 11;29(2):265-273. doi: 10.1007/s10068-019-00649-x. eCollection 2020 Feb.

DOI:10.1007/s10068-019-00649-x
PMID:32064135
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6992804/
Abstract

Steamed ginger ethanolic extract (SGE) is a product with a high 6-shogaol contents and is thought to be more potent than other ginger products. We conducted a 12-week, randomized, double-blind, placebo-controlled clinical trial to determine the effects of SGE on weight and body fat loss. Eighty healthy obese participants were recruited and randomly divided into the SGE and placebo groups. The outcome measures comprised indicators of efficacy (body weight, body mass index, body composition, and blood markers) and safety. Following the supplementation period, mean body weight, body mass index, and body fat level were significantly lower in the SGE group than in the placebo group. No clinically significant changes were observed for any safety parameter. These results suggest that SGE is a potent anti-obesity agent that does not cause significant side effects. Therefore, SGE supplementation combined with lifestyle modification could be effective in the management of body weight and fat mass.

摘要

蒸制生姜乙醇提取物(SGE)是一种6-姜辣素含量高的产品,被认为比其他生姜产品更具效力。我们进行了一项为期12周的随机、双盲、安慰剂对照临床试验,以确定SGE对体重和体脂减少的影响。招募了80名健康肥胖参与者,并将他们随机分为SGE组和安慰剂组。结果指标包括疗效指标(体重、体重指数、身体成分和血液指标)和安全性指标。在补充期结束后,SGE组的平均体重、体重指数和体脂水平显著低于安慰剂组。未观察到任何安全参数有临床显著变化。这些结果表明,SGE是一种有效的抗肥胖剂,不会引起显著的副作用。因此,补充SGE并结合生活方式的改变可能对体重和体脂管理有效。