Melbourne Dental School, The University of Melbourne, Carlton, Victoria, Australia.
School of Pharmacy, University of Queensland, Woolloongabba, Queensland, Australia.
Aust Dent J. 2020 Jun;65(2):118-130. doi: 10.1111/adj.12751. Epub 2020 Mar 13.
The risk of postoperative bleeding is a daily concern for many general dental practitioners. A thorough medical and medication history must be taken to consider all risk factors, particularly drugs, that contribute to bleeding risk. While the risk from drugs such as aspirin, warfarin and clopidogrel are well known, the extent to which new antiplatelet agents and direct oral anticoagulants affect bleeding risk is less well understood. In addition, there are drugs other than antithrombotics, such as antidepressants and complementary medicines that also impair haemostasis. The aim of this paper is to provide dentists with an updated overview of the drugs commonly encountered in general dental practice that can contribute to a patient's postoperative bleeding risk.
术后出血的风险是许多普通牙科医生每天都关心的问题。必须进行彻底的医疗和用药史记录,以考虑所有增加出血风险的因素,特别是药物因素。虽然阿司匹林、华法林和氯吡格雷等药物的风险众所周知,但新型抗血小板药物和直接口服抗凝剂对出血风险的影响程度了解得较少。此外,除了抗血栓药物外,还有一些其他药物,如抗抑郁药和补充药物,也会影响止血功能。本文的目的是为牙医提供普通牙科实践中常见的可增加患者术后出血风险的药物的最新概述。