Woolcombe Sarah A, Ball Rebecca E, Patel Jignesh P
Department of Oral Surgery, King´s College Hospital NHS Foundation Trust, UK.
Department of Haematological Medicine, King´s College Hospital NHS Foundation Trust, UK; Institute of Pharmaceutical Science, King´s College London, UK.
Br Dent J. 2022 Apr;232(8):547-554. doi: 10.1038/s41415-022-3999-y. Epub 2022 Apr 22.
Introduction The Scottish Dental Clinical Effectiveness Programme (SDCEP) guidance on the management of dental patients taking anticoagulant or antiplatelet drugs provides recommendations on the management of patients taking direct oral anticoagulants (DOACs). This guidance was developed by a multidisciplinary Guidance Development Group, based on available resources at the time of publication. We aim to describe our experience of managing a cohort of adult patients prescribed DOACs, undergoing dentoalveolar procedures in accordance with the SDCEP guidance, between April 2017 and March 2020.Methods As part of our routine practice, patients received a telephone consultation one week following treatment, to assess any post-operative bleeding. Review of the clinical notes was used to assess clinician adherence to the guidance recommendations.Results In total, 98 patients underwent 119 dentoalveolar procedures. Persistent bleeding followed 17 (14.3%) procedures, of which 11 (9.2%) procedures required specific intervention. Absolute compliance with the recommendations was 43.7%, supporting the recommendation for audit and staff education.Discussion A diagnosis of heart failure and advanced age were identified as contributory factors to post-operative bleeding.Conclusions The SDCEP guidance is safe to follow, with no patients experiencing major haemorrhage. Consulting a medical specialist for patients with heart failure of likely significance, based on the medical or drug history, in addition to those who report an advanced heart failure diagnosis and the frail/older person, could reduce the incidence of post-operative bleeding.
引言 苏格兰牙科临床疗效项目(SDCEP)关于服用抗凝剂或抗血小板药物的牙科患者管理的指南提供了关于服用直接口服抗凝剂(DOACs)患者管理的建议。该指南由一个多学科指南制定小组制定,基于发布时的可用资源。我们旨在描述我们在2017年4月至2020年3月期间,按照SDCEP指南管理一组接受牙槽外科手术的成年DOACs处方患者的经验。
方法 在我们的常规实践中,患者在治疗后一周接受电话咨询,以评估任何术后出血情况。通过查阅临床记录来评估临床医生对指南建议的遵守情况。
结果 共有98名患者接受了119次牙槽外科手术。17例(14.3%)手术后出现持续出血,其中11例(9.2%)需要进行特殊干预。对建议的绝对遵守率为43.7%,这支持了进行审计和开展员工教育的建议。
讨论 心力衰竭和高龄被确定为术后出血的促成因素。
结论 遵循SDCEP指南是安全的,没有患者发生大出血。除了那些报告有晚期心力衰竭诊断以及体弱/老年患者外,根据病史或用药史,对于可能有重要意义的心力衰竭患者咨询医学专家,可能会降低术后出血的发生率。