Samsun Psychiatry and Neurology Hospital, Turkey.
Gulhane Research and Training Hospital, Keçiören, Turkey.
J Atten Disord. 2021 Jul;25(9):1321-1330. doi: 10.1177/1087054720902846. Epub 2020 Feb 17.
This study investigated the effects of sluggish cognitive tempo (SCT), other psychiatric symptoms, age, dose, and pretreatment ADHD severity on methylphenidate (MPH) treatment response among ADHD children in both home and school. In addition, the predictors of the MPH-SCT treatment response were examined. : One hundred eighty-five (6-12 years old) ADHD children who were treated with MPH included in the study. MPH improved SCT total and SCT-Daydreaming scores both at home and school while improved SCT-Sluggish scores in only school. Higher pretreatment Daydreaming score predicted lower treatment response for inattention ( = .301, = .002), and higher Daydreaming-Sluggish scores predicted lower treatment response for total ADHD symptoms at school ( = .456, = .006; = .888, = .04, respectively). Also higher oppositional defiant disorder symptoms have negative effects on MPH treatment response in ADHD. Older age positively affected the MPH-SCT treatment response in paternal and teacher ratings. : SCT symptoms have negative effects on MPH treatment response at school.
这项研究调查了在家庭和学校环境中， sluggish cognitive tempo（SCT）、其他精神症状、年龄、剂量和 ADHD 严重程度对 ADHD 儿童接受哌醋甲酯（MPH）治疗反应的影响。此外，还探讨了 MPH-SCT 治疗反应的预测因素。研究纳入了 185 名（6-12 岁）接受 MPH 治疗的 ADHD 儿童。MPH 改善了 SCT 总分和白日梦得分，无论是在家庭还是学校环境中，而在学校环境中仅改善了 SCT 缓慢得分。较高的白日梦得分预示着对注意力不集中的治疗反应较低（ =.301， =.002），而较高的白日梦-缓慢得分预示着 ADHD 症状总分在学校的治疗反应较低（ =.456， =.006； =.888， =.04，分别）。此外，对立违抗障碍症状越严重，对 ADHD 儿童的 MPH 治疗反应的负面影响越大。年龄较大对父亲和教师评定的 MPH-SCT 治疗反应有积极影响。结论：SCT 症状对 MPH 治疗反应在学校环境中有负面影响。
