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影响应用负压伤口疗法治疗骨肉瘤术后伤口问题的因素。

Factors affecting postmusculoskeletal tumour surgery wound problem treatment with negative pressure wound therapy.

机构信息

Department of Orthopaedic and Traumatology, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey.

出版信息

Int Wound J. 2020 Jun;17(3):692-700. doi: 10.1111/iwj.13326. Epub 2020 Feb 17.

Abstract

The aim of the study is to investigate the risk factors identified in literature that have been associated with prolonged Negative Pressure Wound Therapy (NPWT). Our study included patients who developed local wound problems after bone or soft tissue sarcoma surgery with negative margin at our clinic between 2012 and 2018 and treated with NPWT. All patients were followed up of at least 6 months. Sex, albumin level, skin infiltration, type of wound problem, postoperative intensive care unit (ICU) requirement, and intraoperative blood loss were found to be influential factors on NPWT > 10 sessions. We conclude that treatment may be prolonged and the necessary precautions need to be taken in patients with an impaired preoperative nutritional condition, with intraoperative high amount of blood loss, and with long postoperative stays in the ICU as well as if the underlying cause for wound problem is an infection.

摘要

本研究旨在探讨文献中已确定的与负压伤口治疗(NPWT)时间延长相关的风险因素。我们的研究纳入了 2012 年至 2018 年间在我院行骨或软组织肉瘤切除术且切缘阴性、并接受 NPWT 治疗后发生局部伤口问题的患者。所有患者均至少随访 6 个月。研究发现,性别、白蛋白水平、皮肤浸润、伤口问题类型、术后入住重症监护病房(ICU)需求以及术中失血量是影响 NPWT 治疗时间超过 10 次的因素。我们得出结论,对于术前营养状况受损、术中失血量较大、术后 ICU 停留时间较长以及伤口问题的根本原因是感染的患者,治疗时间可能会延长,需要采取必要的预防措施。

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