Chmell M J, Schwartz H S
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2550, USA.
J Surg Oncol. 1996 Mar;61(3):185-9. doi: 10.1002/(SICI)1096-9098(199603)61:3<185::AID-JSO4>3.0.CO;2-7.
Adjuvant treatment modalities, nutritional parameters, and allogenic blood transfusions are investigated as possible contributing variables which may adversely affect wound healing after tumor resections for musculoskeletal sarcomas. Statistical analysis determined that preoperative chemotherapy, depressed preoperative hematocrit, and allogenic blood transfusions (probably immunosuppression mediated) were the only significant factors affecting wound healing outcome. Suggestions to improve postoperative infection rates are discussed.
辅助治疗方式、营养参数和异体输血作为可能的影响因素进行了研究，这些因素可能会对肌肉骨骼肉瘤肿瘤切除术后的伤口愈合产生不利影响。统计分析确定，术前化疗、术前血细胞比容降低和异体输血（可能由免疫抑制介导）是影响伤口愈合结果的唯一重要因素。文中还讨论了改善术后感染率的建议。
