Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA.
Yale Cancer Center, New Haven, CT, USA.
Transl Behav Med. 2021 Mar 16;11(2):549-562. doi: 10.1093/tbm/ibaa009.
Energy imbalance increases cancer burden by increasing cancer risk and mortality. Training early career investigators on conducting impactful energy balance and cancer research is needed. We developed a Transdisciplinary Research in Energetics and Cancer (TREC) Training Program for early career investigators. This analysis examined program satisfaction, knowledge gained, publications, and awards among Year 1 participants (i.e., fellows). The program consists of an in-person course, followed by 1 year of mentorship. Faculty and fellows completed precourse and postcourse surveys. Following the mentorship period, we surveyed fellows for TREC-related research productivity, including publications and grant funding attributed to the program. Twenty fellows were accepted into the program: 3 basic, 7 clinical, and 10 population scientists. Sixteen fellows were junior faculty and four were postdoctoral fellows. The course included ~50 lectures, small group sessions, and faculty-fellow sessions. 96.7% of attendees rated the course in the highest categories of "good/very good." Knowledge significantly improved in 37 of 39 research competencies (94.8%). In the 18 months following the course, fellows published 25 manuscripts, with 3 published in journals with impact factor ≥10. Nineteen grants were funded to TREC fellows (i.e., 7 National Institutes of Health awards, 2 American Cancer Society [ACS] awards, and 10 foundation/pilot awards), and 7 fellows received career promotions. The program's impact will be defined by the degree to which TREC fellows produce discoveries that could improve the health of populations at risk for and/or surviving cancer. Upon the conclusion of our fifth year in 2021, we will publicly disseminate the program material.
能量失衡通过增加癌症风险和死亡率增加癌症负担。需要对从事有影响力的能量平衡和癌症研究的早期职业研究人员进行培训。我们为早期职业研究人员制定了跨学科能量学和癌症研究(TREC)培训计划。该分析检查了第一年参与者(即研究员)的计划满意度、获得的知识、出版物和奖项。该计划包括一个实地课程,随后是 1 年的指导。教师和研究员完成了课前和课后调查。在指导期结束后,我们调查了研究员在 TREC 相关研究方面的生产力,包括归因于该计划的出版物和资助资金。20 名研究员被纳入该计划:3 名基础研究员、7 名临床研究员和 10 名人群科学家。16 名研究员是初级教员,4 名是博士后研究员。该课程包括约 50 次讲座、小组会议和教员-研究员会议。96.7%的与会者将课程评为“良好/非常好”。在 39 项研究能力中有 37 项的知识显著提高(94.8%)。在课程结束后的 18 个月内,研究员发表了 25 篇论文,其中 3 篇发表在影响因子≥10 的期刊上。19 项资助授予 TREC 研究员(即 7 项美国国立卫生研究院奖、2 项美国癌症协会[ACS]奖和 10 项基金会/试点奖),7 名研究员获得职业晋升。该计划的影响将取决于 TREC 研究员在多大程度上产生能够改善处于癌症风险中或幸存的人群健康的发现。到 2021 年我们第五年结束时,我们将公开传播该计划的材料。