Department of Liver and General Surgery, Collegium Medicum UMK, Bydgoszcz, Poland.
Department of Oncological Urology, Oncology Centre, Bydgoszcz, Poland.
ANZ J Surg. 2020 Jun;90(6):1119-1124. doi: 10.1111/ans.15740. Epub 2020 Feb 17.
Complete resection is the only potential curative treatment of synchronous colorectal liver metastases. Although simultaneous liver and colon resections became an accepted procedure at specialized centres for selected patients, there is still little data about the long-term results of simultaneous operative procedures compared with those of delayed operations. In this retrospective study, the long-term survival rates of the patients who underwent simultaneous or delayed resections were presented.
A retrospective analysis of liver resections in our institution between 1997 and 2012 was performed. Among 131 patients presented with synchronous colorectal liver metastases, 52 underwent simultaneous and 79 delayed resection. Patients with extrahepatic metastases were excluded, except for 10 patients with metastases limited to liver and lungs that were qualified as resectable.
Age, sex and localization of the primary tumour were similar in the two groups. In the delayed resection group, the majority of colon resections were performed in different hospitals. The frequency of complications did not differ between the groups. The 1, 5 and 10 years survival rates were 77%, 43% and 20% in simultaneous and 86%, 37% and 19% in delayed resection group, respectively. No cancer related deaths occurred after more than 10 years of observation.
The long-term outcome of simultaneous resection of synchronous colorectal liver metastases is comparable to delayed resection.
完全切除是治疗结直肠肝转移同步性的唯一潜在治愈方法。虽然同时进行肝和结肠切除术已成为专门中心为选定患者接受的一种可接受的程序，但与延迟手术相比，同时进行手术的长期结果仍然知之甚少。在这项回顾性研究中，报告了同时或延迟切除的患者的长期生存率。
对 1997 年至 2012 年在我院进行的肝切除术进行了回顾性分析。在 131 例结直肠肝转移同步性患者中，52 例接受了同时切除术，79 例接受了延迟切除术。排除了肝外转移患者，除非 10 例转移灶仅限于肝和肺，这些患者符合可切除条件。
两组患者的年龄、性别和原发肿瘤的部位相似。在延迟切除组中，大多数结肠切除术是在不同的医院进行的。两组并发症的发生率无差异。同时切除术组的 1、5 和 10 年生存率分别为 77%、43%和 20%，延迟切除术组分别为 86%、37%和 19%。观察时间超过 10 年后无癌症相关死亡。
同时切除结直肠肝转移同步性的长期结果与延迟切除相当。
