转录因子 ICE1 通过与 CBF 和 COR 基因启动子结合，在冷胁迫响应中发挥作用。
The transcription factor ICE1 functions in cold stress response by binding to the promoters of CBF and COR genes.
机构信息
Shanghai Center for Plant Stress Biology and CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.
Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN, 47907, USA.
出版信息
J Integr Plant Biol. 2020 Mar;62(3):258-263. doi: 10.1111/jipb.12918.
A recent paper by Kidokoro et al. (2020) in The Plant Cell reported a transgene-dependent transcriptional silencing phenomenon in the dominant ice1-1 Arabidopsis mutant containing the CBF3-LUC reporter, and questioned whether ICE1 may regulate CBF genes and may be involved in plant cold response. Here, we evaluate available evidence supporting the involvement of ICE1 in plant cold response, and provide ChIP-seq data showing ICE1 binding to the promoters of CBF genes and other regulatory genes known to be critical for cold response as well as to the promoters of some COR genes.
最近，Kidokoro 等人在《植物细胞》杂志上发表的一篇论文报道了在含有 CBF3-LUC 报告基因的显性 ice1-1 拟南芥突变体中，依赖于转基因的转录沉默现象，并质疑 ICE1 是否调节 CBF 基因，是否参与植物的冷响应。在这里，我们评估了支持 ICE1 参与植物冷响应的现有证据，并提供了 ChIP-seq 数据，显示 ICE1 结合到 CBF 基因和其他已知对冷响应至关重要的调控基因的启动子上，以及一些 COR 基因的启动子上。
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