Oliveira Renan T G, Simoneti Fernanda S, Agostinho Giovana L P L, Abdalla Beatrice M Z, Locatelli Daniela S, Pincelli Thais, Criado Paulo R
Resident Doctor of Dermatology at Faculty of Medicine of ABC, São Paulo, Brazil.
Resident Doctor of Internal Medicine at Faculty of Medicine of ABC, São Paulo, Brazil.
Dermatol Ther. 2020 May;33(3):e13274. doi: 10.1111/dth.13274. Epub 2020 Mar 2.
Porokeratosis (PK) consists of abnormal keratinization of the epidermis of uncertain etiology and was first described by Mibelli in 1893. Multiple clinical variants of porokeratosis are recognized. The following is a case of a young male who presented more than one form of PK simultaneously. The hallmark of PK is the cornoid lamella, which can be identified in histopathology, and sometimes, as in our case, dermoscopy examination is the clue for diagnosis. This condition is often misdiagnosed and, therefore, not appropriately treated. Several treatment options are available and each clinical form may respond better to a specific therapy. However, consistency in treatment guidelines is still lacking.
汗孔角化症(PK)是一种病因不明的表皮异常角化疾病,于1893年由米贝利首次描述。汗孔角化症有多种临床变体。以下是一名年轻男性同时出现不止一种汗孔角化症形式的病例。汗孔角化症的标志是角样板,这在组织病理学中可以识别,有时,就像我们的病例一样,皮肤镜检查是诊断的线索。这种疾病常常被误诊,因此没有得到恰当治疗。有几种治疗选择,每种临床形式可能对特定治疗反应更好。然而,治疗指南仍缺乏一致性。