Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA.
Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.
Neuromodulation. 2020 Jul;23(5):704-712. doi: 10.1111/ner.13128. Epub 2020 Feb 18.
At least 50% of individuals who suffer a brachial plexus avulsion (BPA) will develop chronic pain, frequently more debilitating than their functional limitations. Similar to other neuropathic pain states, BPA pain is often refractory to pharmacological agents. Despite spinal cord stimulation (SCS) first being used for BPA in 1974, there have been no published literature reviews examining the current evidence of SCS for the treatment of neuropathic pain following BPA. In addition to a clinical review of the literature for this indication, we also share our experience with high-frequency SCS (HF-SCS) for BPA-related pain.
MEDLINE and EMBASE databases were searched. All published articles including at least one BPA individual treated with SCS for pain treatment were included.
The initial search identified 288 articles, of which 13 met inclusion criteria for a total of 41 patients. These patients were primarily male and underwent SCS with reported improved pain scores.
HF-SCS leads were percutaneously placed in two male patients who suffered BPA from traumatic injuries. At follow-ups of 13 and eight months, respectively, both patients continued to report an improvement in their pain.
Despite published reports showing benefit for pain control in patients with BPA, the overall low quality, retrospective evidence included in this review highlights the need for a rigorous prospective study to further address this indication.
至少 50% 的臂丛神经撕脱伤(BPA)患者会发展为慢性疼痛,其严重程度通常甚于功能受限。与其他神经病理性疼痛状态一样,BPA 疼痛常对药物治疗无效。尽管脊髓刺激(SCS)于 1974 年首次用于 BPA,但目前尚无针对 BPA 后神经病理性疼痛的 SCS 治疗的文献综述。除了对该适应证的文献进行临床回顾外,我们还分享了我们使用高频脊髓刺激(HF-SCS)治疗 BPA 相关疼痛的经验。
检索 MEDLINE 和 EMBASE 数据库。纳入所有至少有 1 例 BPA 患者接受 SCS 治疗疼痛的发表文章。
最初的搜索确定了 288 篇文章,其中 13 篇符合纳入标准,共 41 例患者。这些患者主要为男性,接受 SCS 治疗后疼痛评分有所改善。
2 例因创伤性损伤导致 BPA 的男性患者经皮放置 HF-SCS 电极。分别在 13 个月和 8 个月的随访中,两名患者均持续报告疼痛改善。
尽管有报道称 BPA 患者的疼痛控制有获益,但本综述纳入的总体质量较低的回顾性证据突出表明,需要一项严格的前瞻性研究来进一步解决这一适应证。